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| 2-(TRIMETHYLSILYL)ETHANESULFONAMIDE, 90% Basic information |
| 2-(TRIMETHYLSILYL)ETHANESULFONAMIDE, 90% Chemical Properties |
Melting point | 81-87 °C | Boiling point | 253.0±42.0 °C(Predicted) | density | 1.057±0.06 g/cm3(Predicted) | solubility | Soluble in benzene, chloroform, dichloromethane,
ether, methanol and toluene. | pka | 10.99±0.60(Predicted) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26 | RIDADR | UN 3335 | WGK Germany | 3 |
| 2-(TRIMETHYLSILYL)ETHANESULFONAMIDE, 90% Usage And Synthesis |
Uses | 2-Trimethylsilylethanesulfonyl amide is a useful reagent for introduction of a SES-protected nitrogen functionality, which can be cleaved with fluoride ion.
| Uses | 2-(Trimethylsilyl)ethanesulfonamide is a source of nucleophilic nitrogen that can react in manifold
ways with electrophiles prior to removal of SES group with fluoride ion. It participates in the following reactions: Preparation of N-Sulfonylimines, Mitsunobu Reactions, Azaglycosylation Chemistry, Preparation of Sulfodiimides, Preparation of (N-SES-imino)phenyliodinane etc. | Preparation | 2-(Trimethylsilyl)ethanesulfonamide is prepared by reaction of 2-(trimethylsilyl)
ethanesulfonyl chloride (accessible from the commercially
available sodium salt of the corresponding sulfonic acid or starting
from vinyl trimethylsilane) with gaseous ammonia (eq 1). |
| 2-(TRIMETHYLSILYL)ETHANESULFONAMIDE, 90% Preparation Products And Raw materials |
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