Crisaborole intermediate

Crisaborole intermediate Basic information
Product Name:Crisaborole intermediate
Synonyms:5-(4-(aminomethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine;Crisaborole Impurity 34;Benzenemethanamine, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
CAS:1187230-70-1
MF:C14H14BNO3
MW:255.08
EINECS:
Product Categories:
Mol File:1187230-70-1.mol
Crisaborole intermediate Structure
Crisaborole intermediate Chemical Properties
Boiling point 417.2±55.0 °C(Predicted)
density 1.28±0.1 g/cm3(Predicted)
pka7.04±0.20(Predicted)
Safety Information
MSDS Information
Crisaborole intermediate Usage And Synthesis
Uses4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine is used as a research tool in the assessment of its benzoxaborole moiety to serve as a hinge-binding scaffold for ROCK inhibition; playing a role in SMC relaxation in rat aorta and guinea pig trachea.
Crisaborole intermediate Preparation Products And Raw materials

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