| | Glycolonitrile Basic information |
| Product Name: | Glycolonitrile | | Synonyms: | cyanomethanol;HYDROXYACETONITRILE;GLYCOLONITRILE;GLYCOLIC ACID NITRILE;FORMALDEHYDE CYANHYDRIN;2-Hydroxymethylnitrile;Glykolonitril;HOCH2CN | | CAS: | 107-16-4 | | MF: | C2H3NO | | MW: | 57.05 | | EINECS: | 203-469-1 | | Product Categories: | | | Mol File: | 107-16-4.mol |  |
| | Glycolonitrile Chemical Properties |
| Hazard Codes | T+ | | Risk Statements | 26/27/28 | | Safety Statements | 36/37/39-45-36/37-28 | | RIDADR | UN 3276 6.1/PG 1 | | WGK Germany | - | | RTECS | AM0350000 | | HazardClass | 6.1(a) | | PackingGroup | I | | Hazardous Substances Data | 107-16-4(Hazardous Substances Data) | | Toxicity | mouse,LCLo,inhalation,27ppm/8H (27ppm),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE,"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 290, 1969. |
| | Glycolonitrile Usage And Synthesis |
| Chemical Properties | light yellow liquid (typically available as a concentrated | | Chemical Properties | Formaldehyde cyanohydrin is a colorless,
odorless, oily liquid. Sweet taste (very highly toxic; do not
test). | | Uses | Solvent and organic intermediate. | | Production Methods | Glycolonitrile is the result of reaction between formaldehyde
and aqueous sodium cyanide in the presence of mineral acid. | | Definition | ChEBI: Glycolonitrile is an cyanohydrin that is acetonitrile in which one of the hydrogens has been replaced by a hydroxy group. | | General Description | Odorless colorless oil with a sweetish taste. Used in the manufacture of intermediates in pharmaceutical production, as a component of synthetic resins, as a chemical intermediate for organic compounds, and as a solvent. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | Glycolonitrile may undergo spontaneous and violent decomposition. Traces of alkali (base) promote violent polymerization [Lewis]. | | Hazard | Toxic by ingestion, inhalation, and skin
absorption. | | Health Hazard | Extremely toxic, exposure by any route should be avoided; may have fatal consequences; death from asphyxiation may occur similar to that resulting from hydrogen cyanide. | | Fire Hazard | Moderate explosion hazard when exposed to heat or by spontaneous chemical reaction in the presence of alkalies if uninhibited. When heated to decomposition, Glycolonitrile emits highly toxic fumes of cyanide and nitrogen oxides. Unstable, may explode on standing. Hazardous polymerization may occur. avoid the presence of alkalis, and exposure to heat. | | Potential Exposure | Formaldehyde cyanohydrin is used in
the manufacture of intermediates in pharmaceutical produc tion and as a component of synthetic resins as a chemical
intermediate for organic compounds, and as a solvent. | | Shipping | UN3276 Nitriles, liquid, toxic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required, Potential Inhalation Hazard (Special
Provision 5). UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. | | Incompatibilities | Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides, and exposure to heat.
Unless stabilized with a weak acid solution, traces of alka lis may cause violent polymerization. |
| | Glycolonitrile Preparation Products And Raw materials |
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