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| | Myristicin Basic information |
| | Myristicin Chemical Properties |
| Melting point | -20℃ | | Boiling point | bp40 173° | | density | d2020 1.1437 | | refractive index | nD20 1.54032 | | storage temp. | 2-8°C | | solubility | Soluble in acetone, ethanol and methanol; | | form | oil | | color | clear, light yellow | | Odor | at 100.00 %. spicy warm balsamic woody | | Odor Type | spicy | | Water Solubility | insoluble in water | | BRN | 166218 | | Stability: | Light Sensitive | | LogP | 2.586 (est) | | CAS DataBase Reference | 607-91-0(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-(607-91-0) |
| Risk Statements | 52/53 | | Safety Statements | 61 | | RIDADR | UN 3082 9/PG 3 | | WGK Germany | 1 | | RTECS | CY2625000 | | F | 10-23 | | Hazardous Substances Data | 607-91-0(Hazardous Substances Data) | | Toxicity | A naturally occurring
methylenedioxyphenyl compound found in nutmeg. It has
been suggested that myristicin may be responsible, in whole or
in part, for the toxicity of nutmeg. The spice (5-15 g) causes
symptoms similar to atropine poisoning: flushing of the skin,
tachycardia, absence of salivation, and excitation of the CNS.
Euphoria and hallucinations have given rise to abuse of this
material. As a methylenedioxyphenyl compound, myristicin
gives rise to a type III spectrum with reduced cytochrome
P450 and can inhibit monooxygenations catalyzed by this cytochrome. |
| | Myristicin Usage And Synthesis |
| Description | Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects. Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma. This product is intended for forensic and research purposes. | | Chemical Properties | Crystalline phenolic ether with a strongodor. | | Uses | A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells | | Definition | The chief substance inthe ripe seeds of nutmeg (Myristica fragrans).It reduces the levels of cytochrome p-450 andinhibits monooxygenations catalyzed by thisenzyme. | | Hazard | Poison; moderately toxic; mutagen. |
| | Myristicin Preparation Products And Raw materials |
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