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| | 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Basic information |
| Product Name: | 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione | | Synonyms: | AURORA KA-4912;1,3-DIMETHYL-6-AMINOURACIL;1,3-DIMETHYL-4-AMINOURACIL;1,3-DIMETHYL-2,6-DIOXO-4-AMINOTETRAHYDROPYRIMIDINE;4-AMINO-1,3-DIMETHYLURACIL FOR SYNTHESIS;6-AMINO-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONE;6-AMINO-1,3-DIMETHYLURACIL;6-AMINO-1,3-DIMETHYLURICIL | | CAS: | 6642-31-5 | | MF: | C6H9N3O2 | | MW: | 155.15 | | EINECS: | 229-662-0 | | Product Categories: | Amines;Building Blocks;Heterocyclic Building Blocks;Pyrimidines;bc0001 | | Mol File: | 6642-31-5.mol |  |
| | 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Chemical Properties |
| Melting point | 295 °C (dec.) (lit.) | | Boiling point | 243.1±43.0 °C(Predicted) | | density | 1.288±0.06 g/cm3(Predicted) | | vapor pressure | 0Pa at 25℃ | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | 6g/l | | form | Solid | | pka | 5.17±0.70(Predicted) | | color | Pale Beige | | PH | 6.9 (100g/l, H2O, 20℃) | | Water Solubility | 7.06g/L(25 ºC) | | InChIKey | VFGRNTYELNYSKJ-UHFFFAOYSA-N | | LogP | -0.4 at 20℃ | | CAS DataBase Reference | 6642-31-5(CAS DataBase Reference) | | EPA Substance Registry System | 2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl- (6642-31-5) |
| | 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Usage And Synthesis |
| Uses | 6-Amino-1,3-dimethyluracil is used as a reagent in the synthesis of new pyrimidine and caffeine derivatives that display highly potential antitumor activity. It is also used as a starting material in the synthesis of fused pyrido-pyrimidines. |
| | 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Preparation Products And Raw materials |
| Raw materials | Acetic anhydride-->1,3-Dimethylurea-->2-cyano-N-methyl-N-[(methylamino)carbonyl]acetamide-->6-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBALDEHYDE-->Solvent Yellow 93-->5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one | | Preparation Products | 1,3,7-TRIMETHYLURIC ACID-->Nifekalant hydrochloride-->6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE-->4,6-Dimethyl-1H-1,2,3-triazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione-->2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]--->Methanimidamide, N,N-dimethyl-N'-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)--->8-Dimethylaminotheophylline |
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