PICROSIDE I

PICROSIDE I Basic information
Product Name:PICROSIDE I
Synonyms:PICROSIDE I;beta-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha]]-;Picroside-Ⅰ;6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-;β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-;[1aS-[1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha]]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl 6-(3-phenyl-2-propenoate) beta-D-glucopyranoside;β-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-;PICOLINIC ACID(P)
CAS:27409-30-9
MF:C24H28O11
MW:492.47
EINECS:248-445-1
Product Categories:Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:27409-30-9.mol
PICROSIDE I Structure
PICROSIDE I Chemical Properties
Boiling point 778.6±60.0 °C(Predicted)
density 1.56±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility ethanol: soluble1mg/mL, clear, colorless
pka12.70±0.70(Predicted)
form powder
color White
InChIKeyBSYHSWKTXMTFNF-NTLZGZQOSA-N
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29389090
MSDS Information
PICROSIDE I Usage And Synthesis
DescriptionPicroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas. Picroside I is an iridoid glycoside found in picroliv. By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver. Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM. At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.
UsesPicroside I acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis.
PICROSIDE I Preparation Products And Raw materials
4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97 3-METHYLTETRAHYDROPYRAN TRANS-2-METHYLCYCLOPENTANOL Isobutyl cinnamate (TETRAHYDRO-PYRAN-3-YL)-METHANOL 7-ACETOXY-1-HEPTENE (R)-(-)-Methyl glycidyl ether PICROSIDE I Picroside III 1,3-CYCLOPENTANEDIOL ETHYL GLYCIDYL ETHER (S)-2-Methyl Glycidol 2,3-EPOXY-2-METHYLBUTANE DI(PROPYLENE GLYCOL) PROPYL ETHER 2-Methoxyethyl acrylate 2-Methyl-2,3-epoxy-1-propanol CROTONIC ACID ISOPROPYL ESTER ISO-AMYL-CROTONATE

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