ChemicalBook Product Catalog Biochemical Engineering Nucleoside drugs Deoxynucleotides and their analogs 5'-CHLORO-5'-DEOXYADENOSINE

5'-CHLORO-5'-DEOXYADENOSINE

5'-CHLORO-5'-DEOXYADENOSINE Basic information
Product Name:5'-CHLORO-5'-DEOXYADENOSINE
Synonyms:5'-CHLORO-5'-DEOXYADENOSINE;5-CHLORO-5-DEOXYADENOSINE HYDRATE;5'-CHLORO-5'-DEOXYADENOSINE MONOHYDRATE;5’-chloro-5’-deoxy-adenosin;5'-CHLORO-5'-DEOXY-D-ADENOSINE;5'-Deoxy-5'-chloroadenosine;5'-Cl-5'-deoxyadenosine;Adenosine,5'-chloro-5'-deoxy-
CAS:892-48-8
MF:C10H12ClN5O3
MW:285.69
EINECS:
Product Categories:
Mol File:892-48-8.mol
5'-CHLORO-5'-DEOXYADENOSINE Structure
5'-CHLORO-5'-DEOXYADENOSINE Chemical Properties
Melting point 187 °C (exothermic decomp onset @144.5 C)(lit.)
Boiling point 645.6±65.0 °C(Predicted)
density 2.03±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO (Slightly), Water (Slightly, Heated)
pka13.03±0.70(Predicted)
form Solid
color Off-White to Light Beige
Safety Information
WGK Germany 3
RTECS AU7357200
MSDS Information
ProviderLanguage
SigmaAldrich English
5'-CHLORO-5'-DEOXYADENOSINE Usage And Synthesis
Uses5''-Deoxy-5''-chloroadenosine is an intermediate in the synthesis of 5''-Deoxy-5''-(methylthio)adenosine (D242600), a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways.
DefinitionChEBI: 5'-chloro-5'-deoxyadenosine is a member of adenosines. It is functionally related to an adenosine.
5'-CHLORO-5'-DEOXYADENOSINE Preparation Products And Raw materials
Preparation Products5'-DEOXY-5'-METHYLTHIOADENOSINE-->5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE-->S-adenosyl-3-thiopropylamine-->5'-deoxy-5'-fluoroadenosine-->S-ADENOSYL-L-CYSTEINE
2-CHLORO 2'-DEOXYADENOSINE 5'-MONOPHOSPHATE, DISODIUM SALT, [8-3H]- 5-CHLOROPENTYLAMINE 5'-CHLORO 5'-DEOXYADENOSINE, [8-14C]-,2-CHLORO 2'-DEOXYADENOSINE, [8-14C]- Adenine hydrochloride 2-Chloro-2'-deoxyadenosine 5'-Triphosphate, Tetralitium salt 2-(2-Chloroethoxy)ethanol 5-Chloropentanol (S)-1-Chloro-2-propanol (S)-(+)-3-Chloro-1,2-propanediol 8-CHLORO-2'-DEOXYADENOSINE-5'-TRIPHOSPHATE LITHIUM SALT 2-CHLORO 2'-DEOXYADENOSINE 5'-MONOPHOSPHATE, DISODIUM SALT, [8-14C]- 2-CHLORO-2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, TETRALITHIUM SALT 5'-CHLORO-5'-DEOXYADENOSINE (S)-3-AMINO-1,2-DIHYDROXYPROPANE HYDROCHLORIDE 1-(2-Chloroethoxy)propane 2-CHLORO 2'-DEOXYADENOSINE, [8-3H]- 2-chloro-2'-deoxyadenosine triphosphate Adenine hydrochloride hemihydrate
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