ChemicalBook Product Catalog Surfactant Non-ionic surfactants Polyol ester type Polyoxyethylene lauryl ether

Polyoxyethylene lauryl ether

Polyoxyethylene lauryl ether Basic information
Description Reference
Product Name:Polyoxyethylene lauryl ether
Synonyms:Brij|r L23;BRIJ 35 FOR SYNTHESIS;C12E23;Fatty alcohol polyoxyethylene ether;GENAPOL(R) C-100, DETERGENT;GENAPOL(R) X-080;GENAPOL(R) X-080, DETERGENT;GENAPOL(R) X-100
CAS:9002-92-0
MF:C58H118O24
MW:1199.55
EINECS:500-002-6
Product Categories:Detergents for Cell Lysis;DetergentsNative Protein Sample Preparation;Biochemistry;Cell Lysis and Protein Extraction Reagents;Core Bioreagents;Research Essentials;Ether Type (Surfactants);Ethylene Glycols & Monofunctional Ethylene Glycols;Functional Materials;Monofunctional Ethylene Glycols;Nonionic Surfactants;Surfactants;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);9002-92-0
Mol File:9002-92-0.mol
Polyoxyethylene lauryl ether Structure
Polyoxyethylene lauryl ether Chemical Properties
Melting point 41-45 °C(lit.)
Boiling point 100 °C(lit.)
density 0.99 g/mL±0.002 g/mL at 20 °C
vapor pressure <1 mm Hg ( 20 °C)
refractive index n20/D 1.461
Fp >230 °F
storage temp. Store below +30°C.
solubility H2O: 40 mg/mL at 20 °C, clear, colorless
form Waxy Pellets
pka0[at 20 ℃]
color White
OdorOdorless
PH5.5-7.0 (100g/l, H2O, 20℃)
PH Range5.5 - 7.5
Water Solubility soluble
FreezingPoint 35.0 to 40.0 ℃
Merck 14,7558
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
LogP2.26 at 25℃
EPA Substance Registry SystemPolyethylene glycol monododecyl ether (9002-92-0)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-41-36/37/38-38-37/38-36
Safety Statements 26-39-37/39-36/37/39-36-24/25
RIDADR UN 3082 9/PG 3
WGK Germany 3
RTECS MD0875000
F 3
TSCA Yes
HS Code 34021300
HS Code 38220000
Hazardous Substances Data9002-92-0(Hazardous Substances Data)
ToxicityLD50 in mice (mg/kg): 1170 orally, 125 i.v. (Zipf)
MSDS Information
ProviderLanguage
SigmaAldrich English
Polyoxyethylene lauryl ether Usage And Synthesis
DescriptionAs a non-ionic surfactant, polyoxyethylene lauryl ether has excellent washing, emulsifying, dispersing, wetting, and solubilizing functions. It also shows strong foaming ability, easy rinsing performance, and excellent detergency. Because this substance acts as one of the lowest irritant species among various surfactants, it is often selected as raw material for mild detergents, shampoos (such as baby shampoos), bath lotion, cleansing milk, and cosmetics. In addition, this chemical may function as emulsifier, softener, wetting agent, and foaming agent. In terms of solubilizing function, this product has been demonstrated to assist in solubilization of steroid hormones, benzoic acid derivatives, and barbiturates.1-3 Besides, when used as surfactant emulsifier, polyoxyethylene lauryl ether is proved to be an active agent for preparing nanoemulsions for food applications.4
Reference
  1. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF STEROID-HORMONES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2832-2837.
  2. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF BENZOIC-ACID DERIVATIVES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2824-2831.
  3. Ikeda, K.; Kato, K.; Tukamoto, T., SOLUBILIZATION OF BARBITURATES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1971, 19, 2510-+.
  4. Silva, H. D.; Cerqueira, M. A.; Vicente, A. A., Nanoemulsions for Food Applications: Development and Characterization. Food Bioprocess Technol. 2012, 5, 854-867.
Chemical PropertiesWhite or almost white, unctuous and hygroscopic mass, melting at 24 °C into a colourless or yellowish, viscous liquid.
UsesBrij L23 is a a pharmaceutical compound used in the schlerotherapy treatments, in those suffering from blood vessel malformations and mutations.
UsesSolvent; nonionic emulsifier; pharmaceutic aid (surfactant); spermaticide.
UsesEthosperse(R) LA-4 is a medium range HLB, ethoxylated, nonionic ether of lauryl alcohol with broad range pH stability. It is suggested for use as an emulsifier in cosmetics to add body and texture (humectant), in household products and in lubricants.
Brand nameBrij 30 (ICI Americas).
General DescriptionClear colorless to light yellow viscous liquid. Colorless at 266°F; brown at 644°F. Bland odor.
Air & Water ReactionsWater soluble.
Reactivity ProfilePolyoxyethylene lauryl ether is incompatible with strong oxidizing agents and strong bases.
Fire HazardPolyoxyethylene lauryl ether is combustible.
Flammability and ExplosibilityNotclassified
Biochem/physiol ActionsBrij? L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.
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