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| | 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL Basic information |
| | 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL Chemical Properties |
| Boiling point | 348.61°C (rough estimate) | | density | 1.1599 (rough estimate) | | refractive index | 1.4830 (estimate) | | Fp | 9℃ | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | neat | | pka | 13.54±0.20(Predicted) | | color | Pale Yellow to Yellow |
| | 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL Usage And Synthesis |
| Chemical Properties | Oil | | Uses | A metabolite of NNK (Cat. #M325750), a tobacco-specific nitrosamine. | | Definition | ChEBI: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol is a member of the class of nitrosamines that is butan-1-ol substituted by a pyridin-3-yl group at position 1 and by a methyl(nitroso)amino group at position 4. It is a major metabolite of nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), which is a carcinogen found in tobacco and responsible for inducing lung cancer in smokers. It has a role as a biomarker, a human urinary metabolite and a carcinogenic agent. It is a member of pyridines, a nitrosamine and a secondary alcohol. It is functionally related to a 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one. | | General Description | This certified Snap-N-Spike? solution is suitable for use as starting material in calibrators and controls for nicotine testing, environmental monitoring, or clinical and diagnostic testing of nicotine biomarkers by LC-MS/MS or GC/MS. NNAL is a metabolite of NNK or 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone. Measurement of NNAL levels in urine is a reliable way to determine NNK exposure in smokers, non-smokers exposed to environmental tobacco smoke (ETS), or users of smokeless tobacco products such as chewing tobacco or snuff. |
| | 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL Preparation Products And Raw materials |
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