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Apremilast Impurity 15

Apremilast Impurity 15 Basic information
Product Name:Apremilast Impurity 15
Synonyms:(S)-3-Acetamido-2-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl ) carbamoyl)benzoic Acid;Apremilast Impurity 3 (S)-3-Acetamido-2-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl ) carbamoyl)benzoic Acid;Apremilast impurity HS093316;Benzoic acid, 3-(acetylamino)-2-[[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]amino]carbonyl]-;Apremilast Impurity 59;Apremilast Impurity 80;3-(Acetylamino)-2-[[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]amino]carbonyl]benzoic Acid (Apremilast Benzoic Acid);Apremilast Benzoic Acid DISCONTINUED PLEASE SEE A729715
CAS:2096492-41-8
MF:C22H26N2O8S
MW:478.52
EINECS:
Product Categories:
Mol File:2096492-41-8.mol
Apremilast Impurity 15 Structure
Apremilast Impurity 15 Chemical Properties
Melting point >125°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Very Slightly, Heated)
form Solid
color Off-White to Pale Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
Apremilast Impurity 15 Usage And Synthesis
Uses(αS)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-benzenemethanamine is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis.
Apremilast Impurity 15 Preparation Products And Raw materials
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Apremilast Impurity 28 Apremilast Impurity 25 Apremilast-d8 Apremilast impurity 18 Apremilast Impurity 1 Apremilast Impurity E Apremilast Impurity 21 Apremilast Apremilast Impurity 1/2 Apremilast Impurity 8 Apremilast Impurity 13 3-acetamidophthalic acid (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide (R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide APST-ZA Apremilast Impurity 2 Apremilast Impurity 9
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