RET-IN-1;Pyrazolo[1,5-a]pyridine-3-carbonitrile, 4-[5-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-2-pyrazinyl]-6-[(2R)-2-morpholinylmethoxy]-;RET IN 1,RETIN1
Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
solubility
Soluble in DMSO
pka
8.23±0.40(Predicted)
form
solid
Safety Information
MSDS Information
LOXO-292 Usage And Synthesis
Description
RET-IN-1 is an oral and selective investigational drug in clinical development for the treatment of patients with cancers that harbor abnormalities in the rearranged during transfection (RET) kinase.