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| | L-SELENOCYSTINE Basic information |
| Product Name: | L-SELENOCYSTINE | | Synonyms: | SELENO-L-CYSTINE;(R,R)-3,3'-DISELENO-BIS(2-AMINOPROPIONIC ACID);L-SELENOCYSTINE;3’-diselenodi-l-alanin;l-3,3’-diselenodialanine;3,3'-DISELENO-L-ALANINE;L-SELENOCYSTINE 98%;(R,R)-3,3μ-Diseleno-bis(2-aminopropionic acid), L-Selenocystine | | CAS: | 29621-88-3 | | MF: | C6H12N2O4Se2 | | MW: | 334.09 | | EINECS: | 608-382-6 | | Product Categories: | amino acids | | Mol File: | 29621-88-3.mol |  |
| | L-SELENOCYSTINE Chemical Properties |
| Melting point | 224.5-229.5 °C (lit.) | | Boiling point | 538.3±60.0 °C(Predicted) | | storage temp. | 2-8°C | | solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) | | form | Powder | | pka | 1.69±0.10(Predicted) | | color | Yellow | | optical activity | [α]20/D 28°, c = 1 in NaOH | | BRN | 1969559 | | Stability: | Hygroscopic |
| Hazard Codes | T,N | | Risk Statements | 23/25-33-50/53 | | Safety Statements | 20/21-28-45-60-61 | | RIDADR | UN 3283 6.1/PG 3 | | WGK Germany | 3 | | RTECS | AY6032000 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29319090 |
| Provider | Language |
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ACROS
| English |
| | L-SELENOCYSTINE Usage And Synthesis |
| Description | L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types. | | Chemical Properties | yellow fine powder | | Uses | Seleno-L-cystine can be used for the synthesis of:
- Biologically active selenol compounds.
- Non-natural selenylated diamino acids.
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| | L-SELENOCYSTINE Preparation Products And Raw materials |
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