1-(4-HYDROXYPHENYL)-2-THIOUREA

1-(4-HYDROXYPHENYL)-2-THIOUREA Basic information
Product Name:1-(4-HYDROXYPHENYL)-2-THIOUREA
Synonyms:4-HYDROXYPHENYLTHIOUREA;1-(4-HYDROXYPHENYL)-2-THIOUREA;4-HYDROXYPHENYLTHIOUREA, 98+%;USAF B-75;1-(p-hydroxyphenyl)-2-thio-ure;p-hydroxyphenylthiourea;1-(4-hydroxyphenyl)thiourea;N-(4-Hydroxyphenyl)thiourea
CAS:1520-27-0
MF:C7H8N2OS
MW:168.22
EINECS:
Product Categories:
Mol File:1520-27-0.mol
1-(4-HYDROXYPHENYL)-2-THIOUREA Structure
1-(4-HYDROXYPHENYL)-2-THIOUREA Chemical Properties
Melting point 214 °C
Boiling point 341.5±44.0 °C(Predicted)
density 1.450±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka9.53±0.26(Predicted)
BRN 1102429
InChIInChI=1S/C7H8N2OS/c8-7(11)9-5-1-3-6(10)4-2-5/h1-4,10H,(H3,8,9,11)
InChIKeyQICKOOCQSYZYQB-UHFFFAOYSA-N
SMILESN(C1=CC=C(O)C=C1)C(N)=S
CAS DataBase Reference1520-27-0(CAS DataBase Reference)
Safety Information
Risk Statements 22
Safety Statements 22-36/37
RTECS YT5250000
HazardClass IRRITANT
Toxicitymouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,
MSDS Information
ProviderLanguage
ALFA English
1-(4-HYDROXYPHENYL)-2-THIOUREA Usage And Synthesis
Uses1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.
1-(4-ETHOXYPHENYL)-2-THIOUREA 4-PHENOXYPHENYLTHIOUREA 1-(4-METHOXYPHENYL)IMIDAZOLINE-2-THIONE 1-(4-BENZYLOXYPHENYL)-2-THIOUREA N-(3,4-DIMETHOXYPHENYL)THIOUREA 1-(3,4-METHYLENEDIOXYPHENYL)-2-THIOUREA 1-(4-HYDROXYPHENYL)-2-THIOUREA 4-(4-BENZYLOXYPHENYL)-3-THIOSEMICARBAZIDE N-(5-CHLORO-2,4-DIMETHOXYPHENYL)-N'-METHYLTHIOUREA 1-(3,4,5-TRIMETHOXYPHENYL)-2-THIOUREA 4-METHOXYPHENYLTHIOUREA 4-(3,4-METHYLENEDIOXYPHENYL)-3-THIOSEMICARBAZIDE 1-(2,4-DIMETHOXYPHENYL)-2-THIOUREA N-(4-ETHOXYPHENYL)-N'-ETHYLTHIOUREA 4-(4-METHOXYPHENYL)-3-THIOSEMICARBAZIDE 1-(4-(TRIFLUOROMETHOXY)PHENYL)-2-THIOUREA AURORA 7340 4-(4-PHENOXYPHENYL)-3-THIOSEMICARBAZIDE

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