Methyl 2,5-dihydroxybenzoate

Methyl 2,5-dihydroxybenzoate Basic information
Product Name:Methyl 2,5-dihydroxybenzoate
Synonyms:METHYL GENTISATE;METHYL 2,5-DIHYDROXYBENZOATE;METHYL 3,6-DIHYDROXYBENZOATE;GENTISIC ACID METHYL ESTER;dihydroxybenzoic acid methyl ester;TIMTEC-BB SBB007711;RARECHEM AL BF 0043;2,5-Dihydroxybenzoic acid methyl ester
CAS:2150-46-1
MF:C8H8O4
MW:168.15
EINECS:218-427-8
Product Categories:Aromatic Esters;Acids & Esters;Phenols
Mol File:2150-46-1.mol
Methyl 2,5-dihydroxybenzoate Structure
Methyl 2,5-dihydroxybenzoate Chemical Properties
Melting point 86-88 °C (lit.)
Boiling point 136 °C / 1mmHg
density 1.354±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka9.87±0.18(Predicted)
form Solid
color Off-White to Pale Beige
Stability:Hygroscopic
InChIKeyXGDPKUKRQHHZTH-UHFFFAOYSA-N
LogP1.830 (est)
CAS DataBase Reference2150-46-1(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoic acid, 2,5-dihydroxy-, methyl ester(2150-46-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29182900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Methyl 2,5-dihydroxybenzoate Usage And Synthesis
Usesmethyl gentisate is also known as methyl dihydroxybenzoate. It is a skin-lightening ingredient that acts by inhibiting the melanocyte’s production of tyrosinase. It can be naturally obtained from gentian root.
UsesMethyl 2,5-dihydroxybenzoate (methyl gentisate) may be used as a starting material in the synthesis of euonyminol.
DefinitionChEBI: Methyl 2,5-dihydroxybenzoate is a member of phenols and a benzoate ester.
General DescriptionMethyl 2,5-dihydroxybenzoate (methyl gentisate) is an alkyl ester of gentisic acid. It is reported to show less cytotoxic and mutagenic activity than hydroquinone with a potential to inhibit melanogenesis. It has been synthesized from 2,5-dihydroxybenzoic acid. The crystal structure of the molecule was found to be planar.
METHYL RICINOLEATE Salicylic acid 2'-Hydroxy-3-phenylpropiophenone Protocatechuic acid METHYL JASMONATE Methyl cinnamate CHOLIC ACID METHYL ESTER 2,5-Dihydroxybenzoic acid Kresoxim-methyl 3,5-Dihydroxybenzoic acid METHYL 3,5-DIHYDROXYBENZOATE FATTY ACID METHYL ESTER MIX C8-C22 Methyl acrylate Borneol Methyl acetate Methyl bromide METSULFURON METHYL trans-Methyl crotonate

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