Glycyl-glycyl-glycine

Glycyl-glycyl-glycine Basic information
Product Name:Glycyl-glycyl-glycine
Synonyms:H-GLY-GLY-GLY-OH;L-GLYCYL-GLYCYL-GLYCINE;H2N-GGG-OH;GLYCYL-GLYCYL-GLYCINE;GLY-GLY-GLY;GLY-GLY-GLY PEPTIDE;DIGLYCYLGLYCINE;(([(Aminoacetyl)amino]acetyl)amino)acetic acid
CAS:556-33-2
MF:C6H11N3O4
MW:189.17
EINECS:209-122-0
Product Categories:amino acid;Biochemistry;Oligopeptides;Peptide Synthesis
Mol File:556-33-2.mol
Glycyl-glycyl-glycine Structure
Glycyl-glycyl-glycine Chemical Properties
Melting point 240-250 °C
Boiling point 324.41°C (rough estimate)
density 1.4204 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: 0.5 M at 20 °C, clear, colorless
pka3.225(at 25℃)
form Solid
color White to Off-White
PH4.5-6.0 (25℃, 0.5M in H2O)
Water Solubility Soluble in water (94.6 mg/ml at 20°C), methanol (50 mg/ml), and 80% acetic acid (50 mg/ml).
λmaxλ: 260 nm Amax: 0.15
λ: 280 nm Amax: 0.10
Merck 14,6579
BRN 1711130
InChIKeyXKUKSGPZAADMRA-UHFFFAOYSA-N
CAS DataBase Reference556-33-2(CAS DataBase Reference)
NIST Chemistry ReferenceN-(N-Glycylglycyl)glycine(556-33-2)
Safety Information
WGK Germany 3
3-10
HS Code 29241990
MSDS Information
ProviderLanguage
Glycyl-glycyl-glycine English
SigmaAldrich English
ALFA English
Glycyl-glycyl-glycine Usage And Synthesis
Chemical Propertieswhite crystalline powder
UsesSubstrate for tripeptide aminopeptidase.
UsesGlycyl-glycyl-glycine is used as a model peptide for studies of physicochemical parameters and molecular associations of small peptides. It is also used as a copper chelator.
DefinitionChEBI: A tripeptide in which three glycine units are linked via peptide bonds in a linear sequence.
General DescriptionGly-Gly-Gly or triglycine is a flexible peptide linker with three glycine residues linked by peptide bonds in a linear sequence. Gly-linkers link multiple domains in a single protein without affecting the function of each domain.
Biochem/physiol ActionsSubstrate for reproducible serum protein measurements by the biuret reaction and for the assay of aminotripeptidases.
Purification MethodsCrystallise triglycine from H2O or H2O/EtOH and dry it at 110o. [Yakel & Hughes Acta Cryst 5 847 1952, Lenel et al. Acta Cryst 3 313 1952, Holley & Holley J Am Chem Soc 74 3072 1952, Beilstein 4 III 1198, 4 IV 2469.]
Glycyl-glycyl-glycine Preparation Products And Raw materials
Preparation ProductsBOC-GLY-GLY-GLY-OH
Glycyl-glycyl-glycyl-glycine, Tetraglycine, Triglycyl-glycine,GLYCYL-GLYCYL-GLYCYL-GLYCINE Glycine DL-LEUCYL-GLYCYL-DL-PHENYLALANINE DL-ALANYL-GLYCYL-GLYCINE Z-LEU-GLY-GLY-OH L-ALANYL-L-ALANYL-L-ALANINE METHYL ESTER ACETATE H-GLY-HIS-GLY-OH ALA-ALA-ALA D-LEUCYL-GLYCYL-GLYCINE Tripeptide-1 Glycylglycine GlycineMax Glycyl-glycyl-glycine HIPPURYL-HIS-LEU GLYCYLGLYCYL-D,L-PHENYLALANINE Z-ALA-GLY-GLY-OH L-Alanyl-L-Glutamine EC 2.3.2.2

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