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| | 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Basic information |
| Product Name: | 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE | | Synonyms: | CARBAMAZEPINE 10,11-EPOXIDE;1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE;1A,10BETA-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE;10,11-epoxycarbamazepine;1a,10b-dihydro-6h-dibenz(b,f)oxiren(d)azepine-6-carboxamide;carbamazepine10,11-oxide;carbamazepineepoxide;10,11-Dihydro-10,11-epoxy-5H-dibenzo[b,f]azepine-5-carboxamide | | CAS: | 36507-30-9 | | MF: | C15H12N2O2 | | MW: | 252.27 | | EINECS: | 641-693-5 | | Product Categories: | Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics;Heterocycles | | Mol File: | 36507-30-9.mol | ![1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Structure](CAS/GIF/36507-30-9.gif) |
| | 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Chemical Properties |
| Melting point | 204-206°C | | Boiling point | 390.2±52.0 °C(Predicted) | | density | 1.377±0.06 g/cm3(Predicted) | | Fp | 9℃ | | storage temp. | -20°C | | solubility | Chloroform (Slightly), DMSO (Slightly) | | pka | 13.91±0.20(Predicted) | | form | neat | | color | White |
| | 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A metabolite of Carbamazepine (C175840).
Representative lots contained 1-2% carbamazepine by HPLC. | | Uses | A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC. | | Uses | A metabolite of Carbamazepine.
Representative lots contained 1-2% carbamazepine by HPLC | | Definition | ChEBI: An epoxide and metabolite of carbamazepine. | | General Description | Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine. | | Biochem/physiol Actions | First metabolite of carbamazepine |
| | 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Preparation Products And Raw materials |
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