Pramipexole Dimer Impurity (Mixture of Diastereomers)

Pramipexole Dimer Impurity (Mixture of Diastereomers) Basic information
Product Name:Pramipexole Dimer Impurity (Mixture of Diastereomers)
Synonyms:PRAMIPEXOLE IMPURITY F/(S)-N6,N6-DIPROPYL-4,5,6,7-TETRAHYDROBENZO[D]THIAZOLE-2,6-DIAMINE;2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6,N6-dipropyl-, (6S)-;(S)-Propyl Pramipexole;N6-Propyl pramipexole
CAS:1147937-31-2
MF:C13H23N3S
MW:253.41
EINECS:
Product Categories:
Mol File:1147937-31-2.mol
Pramipexole Dimer Impurity (Mixture of Diastereomers) Structure
Pramipexole Dimer Impurity (Mixture of Diastereomers) Chemical Properties
Melting point >96°C (dec.)
Boiling point 400.9±45.0 °C(Predicted)
density 1.10±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly, Sonicated)
pka8.83±0.20(Predicted)
form Solid
color Pale Yellow to Light Beige
Safety Information
MSDS Information
Pramipexole Dimer Impurity (Mixture of Diastereomers) Usage And Synthesis
Uses(S)- Propyl Pramipexole is (S)-Pramipexole (P700750) analogue. (S)-Pramipexole (P700750) is a dopamine-D2-receptor agonist. Antiparkinsonian. Pramipexole (Mirapex, Mirapexin, Sifrol) is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson''s disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.
Pramipexole Dimer Impurity (Mixture of Diastereomers) Preparation Products And Raw materials
(R)-Pramipexole (S)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine (6S,7S)-2-amino-6-(propylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ol Pramipexole rac-trans-7-Hydroxy Pramipexole 2-N-Propyl Pramipexole Ethyl Pramipexole (6S,7S)-4,5,6,7-tetrahydro-N6-propyl-N7-[(6S)-4,5,6,7-tetrahydro-6-(propylamino)-2-benzothiazolyl]-2,6,7-Benzothiazoletriamine BENZOOXAZOL-2-YLAMINE rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid (S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediaMine Pramipexole dihydrochloride monohydrate N-(3-bromo-4-oxocyclohexyl)acetamide (6S)-N6-[3-[[(6S)-2-Amino-4,5,6,7-tetrahydro-6-benzothiazolyl]amino]-1-ethyl-2-methylpropyl]-4,5,6,7-tetrahydro-2,6-benzothiazolediamine Pramipexole Impurity 15 Pramipexole (R)-N-(2-AMINO-4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-6-YL)-PROPIONAMIDE 2-AMino-6-(propylaMino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one

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