(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine

(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine Basic information
Product Name:(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
Synonyms:(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine;(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine;1-(7,8-Dihydro-napthalen-1-yl)-ethyl]- [3-(3-trifluoromethyl-phenyl)]-amine hydrochloride;(E)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide hydrochloride;(R)-1-(naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethan-1-aminehydrochloride;(R)-1-(phthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethan-1-aminehydrochloride;"(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl);1-Naphthalenemethanamine, 7,8-dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-
CAS:802918-35-0
MF:C22H24F3N
MW:359.4278696
EINECS:
Product Categories:
Mol File:802918-35-0.mol
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine Structure
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine Chemical Properties
Boiling point 427.1±45.0 °C(Predicted)
density 1.138±0.06 g/cm3(Predicted)
pka9.48±0.29(Predicted)
Safety Information
MSDS Information
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine Usage And Synthesis
Uses(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455335) using HPLC.
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine Preparation Products And Raw materials
4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID (R)-1-(Naphthalen-2-yl)ethanamine hydrochloride Cinacalcet Impurity 20 3-(3-METHYLPHENYL)PROPIONIC ACID 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride (R)-1-(naphthalen-1-yl)ethan-1-amine (R)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethanamine hydrochloride 3-(3-Trifluoromethylphenyl)propionic acid Cinacalcet IMpurity CINACALCET (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride 3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid Cinacalcet Impurity 21 (S)-1-(naphthalen-1-yl)ethan-1-amine (R)-1-(5,6-dihydronaphthalen-1-yl)ethan-1-amine (αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide 3-(Trifluoromethyl)cinnamic acid

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