Atorvastatin lactone

Atorvastatin lactone Basic information

Product Name:	Atorvastatin lactone
Synonyms:	1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide;Atorvastatin EPIMp H (USP RCH);Atorvastatin EP IMpurity H;Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide);Diepoxide Atorvastatin Lactone Diepoxide;Atorvastatin Calcium Impurity D;Atorvastatin Impurity H;(RS) Atorvastatin Lactone
CAS:	125995-03-1
MF:	C33H33FN2O4
MW:	540.62
EINECS:
Product Categories:	Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	125995-03-1.mol

Atorvastatin lactone Chemical Properties

Melting point	103-106°C
alpha	D +26.05° (c = 1 in chloroform)
Boiling point	674.8±55.0 °C(Predicted)
density	1.24±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	13.39±0.40(Predicted)
form	Solid
color	White to Light Yellow
Merck	14,864

Safety Information

HS Code

2933.99.7500

MSDS Information

Atorvastatin lactone Usage And Synthesis

Chemical Properties	Slightly Yellow Solid
Uses	Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation
Uses	Atorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.

Atorvastatin lactone Preparation Products And Raw materials

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