ent-Ivabradine Hydrochloride

ent-Ivabradine Hydrochloride Basic information
Product Name:ent-Ivabradine Hydrochloride
Synonyms:ent-Ivabradine Hydrochloride;Ivabradine R-Isomer HCl;3-[3-[[[(7R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one;Ivabradine R-Isomer hydrochloride;I-3015;Ivabradine HCl R-Isomer;3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one);IIvabradine R-Isomer HCl
CAS:148849-68-7
MF:C27H37ClN2O5
MW:505.05
EINECS:
Product Categories:
Mol File:148849-68-7.mol
ent-Ivabradine Hydrochloride Structure
ent-Ivabradine Hydrochloride Chemical Properties
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Light Beige
Stability:Hygroscopic
Safety Information
MSDS Information
ent-Ivabradine Hydrochloride Usage And Synthesis
Uses3,3''-(Propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one) is an impurity of 3,3''-(Propane-1,3-diyl)bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one) (P760340); an impurity in the synthesis of Ivabradine (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also antianginal.
ent-Ivabradine Hydrochloride Preparation Products And Raw materials
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride Ivabradine Impurity 21 HCl Ivabradine-d3 Hydrochloride 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Dehydro Ivabradine Oxalate 8-DeMethyl Ivabradine Ivabradine Impurity 1 Hydrochloride N-DeMethyl Ivabradine Hydrochloride Ivabradine Impurity 1 Hydrochloride 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one Nalfurafine 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one Ivabradine IMpurity Ivabradine Impurity 15 Ivabradine Impurity 16 HCl Ivabradine hydrochloride 3-(3-hydroxypropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one Ivabradine Impurity 5

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