ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine

1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine

1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine Basic information
Product Name:1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine
Synonyms:1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine;Des(Methylpiperazinyl-N-Methyl) IMatinib DiMer IMpurity;Imatinib Impurity E;Imatinib Dimer Impurity;Imatinib bis Impurity;Imatinib Imp.E;Imatinib Impurity E/Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity;Imatinib impurity 13/Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity/1,4-Bis-[4-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]carbamoyl]benzylpiperazine
CAS:1365802-18-1
MF:C52H48N12O2
MW:873.02
EINECS:
Product Categories:Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1365802-18-1.mol
1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine Structure
1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine Chemical Properties
Melting point >213°C (dec.)
density 1.327±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly)
pka12.98±0.70(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine Usage And Synthesis
UsesDes(methylpiperazinyl-N-methyl) Imatinib Dimer is an impurity of Imatinib (Gleevec) (G407000). Imatinib impurity E. It is a COVID19-related research product.
1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine Preparation Products And Raw materials
N-DESMETHYL IMATINIB Imatinib Impurity 7 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Imatinib Meta-methyl-piperazine Impurity IMatinib Para-diaMinoMethylbenzene Guanidine, N-(2-methyl-3-nitrophenyl)- 4-(4-Methylpiperazin-1-ylmethyl)benzoic acid Imatinib (Piperidine)-N-oxide iMatinib related substance B N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE Imatinib (Pyridine)-N-oxide Imatinib Imatinib impurity 31 Guanidine, N-(2-methyl-6-nitrophenyl)- iMatinib related substance C 3-Acetylpyridine Benzamide, 4-(dichloromethyl)-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-
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