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| | 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Basic information |
| Product Name: | 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride | | Synonyms: | 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride;2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride;2-AMino-4-(4-fluoronaphth-1-yl)-6-isopropylpyriMidine Monohydrochloride;MT 500 Hydrochloride;4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine;4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine monohydrochloride;RS 127445 hydrochloride NEW | | CAS: | 199864-86-3 | | MF: | C17H17ClFN3 | | MW: | 317.7883832 | | EINECS: | | | Product Categories: | | | Mol File: | 199864-86-3.mol |  |
| | 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Chemical Properties |
| Melting point | 158 °C | | storage temp. | 2-8°C | | solubility | DMSO: ≥20mg/mL | | form | powder | | color | white to tan |
| Hazard Codes | T | | Risk Statements | 25-36 | | Safety Statements | 26-45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | HS Code | 2933.59.5300 |
| | 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Usage And Synthesis |
| Uses | RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selec
tivity for this receptor as compared to numerous other receptor and ion channel binding sites. | | Uses | RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites. | | storage | Desiccate at +4°C |
| | 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Preparation Products And Raw materials |
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