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Indacaterol interMediate

Indacaterol interMediate Basic information
Product Name:Indacaterol interMediate
Synonyms:(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one;(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)quinolin-2(1H)-one;(R)-8-benzyloxy-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one;5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one;(R)-8-(benzyloxy)-5-(2-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylaMino)-1-hydroxyethyl)quinolin-2(1H)-one;(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1;(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-;Indacaterol Impurity 8
CAS:435273-75-9
MF:C31H34N2O3
MW:482.61
EINECS:
Product Categories:
Mol File:435273-75-9.mol
Indacaterol interMediate Structure
Indacaterol interMediate Chemical Properties
Melting point 78-82°C
Boiling point 734.1±60.0 °C(Predicted)
density 1.23
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka10.86±0.70(Predicted)
color Off-White to Pale Yellow
Safety Information
MSDS Information
Indacaterol interMediate Usage And Synthesis
Uses5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone is used as a reactant in the preparation of Indacaterol (I499745), a β-adrenoreceptor agonist.
Indacaterol interMediate Preparation Products And Raw materials
Preparation ProductsIndacaterol
2-(2-butyl-4-hydroxy-6-MethylpyriMidin-5-yl)-N,N-diMethylacetaMide Indacaterol Impurity 12 (S)-Indacaterol Indacaterol Impurity 3 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide 2(1H)-Quinolinone, 5,5'-[[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)imino]bis(1-hydroxy-2,1-ethanediyl)]bis[8-(phenylmethoxy)- Fimasartan Indacaterol Impurity 11 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride Triphenylmethanol 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide Indacaterol Impurity 22 METHYL TRIPHENYLMETHYL ETHER 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Indacaterol Maleate Indacaterol 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 2-(2-butyl-4-Methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-1,6-dihydropyriMidin-5-yl)-N,N-diMethylethanethioaMide
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