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| Product Name: | D(-)-allo-Threonine | | Synonyms: | (r)-allothreonine;Allothreonine, D-;d-allothreonin;(2R,3S)-2-Amino-3-hydroxybutyric acid~H-D-Thr-OH;(2S,3S)-2-amino-3-hydroxy-butanoic acid;(2R,3R)-2-Amino-3-hydroxybutanoic acid;D(-)-allo-Threonine,99%;(2R,3R)-(-)-ALLO-THREONINE | | CAS: | 24830-94-2 | | MF: | C4H9NO3 | | MW: | 119.12 | | EINECS: | 246-488-0 | | Product Categories: | Threonine [Thr, T];Amino Acids | | Mol File: | 24830-94-2.mol |  |
| | D(-)-allo-Threonine Chemical Properties |
| Melting point | 276 °C (dec.)(lit.) | | alpha | -33.5 º (c=1, 1N HCl 24 ºC) | | Boiling point | 222.38°C (rough estimate) | | density | 1.3126 (rough estimate) | | refractive index | -10 ° (C=5, H2O) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Water (Slightly) | | pka | 2.19±0.10(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | soluble | | BRN | 1721644 | | InChIKey | AYFVYJQAPQTCCC-PWNYCUMCSA-N | | CAS DataBase Reference | 24830-94-2(CAS DataBase Reference) | | NIST Chemistry Reference | D-allothreonine(24830-94-2) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | BA4050000 | | HS Code | 29225090 | | Toxicity | rat,LD50,intraperitoneal,6910mg/kg (6910mg/kg),BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)LUNGS, THORAX, OR RESPIRATION: DYSPNEA,Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956. |
| | D(-)-allo-Threonine Usage And Synthesis |
| Description | D(-)-allo-Threonine is an isomer of threonine. It is found as a constituent of an increasing group of biologically active peptides. Stereocontrolled syntheses of chiral and racemic key intermediates to thienamycin can be achieved from d-allo-threonine and trans-crotonic acid.
| | References | https://www.alfa.com/en/catalog/H27050/
http://www.sigmaaldrich.com/catalog/product/sigma/t9643?lang=en®ion=US
| | Chemical Properties | white crystalline powder | | Uses | They are found as constituents of an increasing group of biologically active peptides. Stereocontrolled syntheses of chiral and racemic key intermediates to thienamycin from d-allo-threonine and trans-crotonic acid. | | Definition | ChEBI: D-allothreonine is the D-enantiomer of allothreonine. It occurs as a component of peptido-lipids in certain bacteria. It has a role as a bacterial metabolite. It is an allothreonine and a D-alpha-amino acid. It is an enantiomer of a L-allothreonine. It is a tautomer of a D-allothreonine zwitterion. | | Purification Methods | Recrystallise D-allothreonine from aqueous EtOH or 50% EtOH. [Elliot J Chem Soc 62 1950, Birnbaum et al. J Biol Chem 194 455 1952, IR: Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 1961, Beilstein 4 IV 3170.] |
| | D(-)-allo-Threonine Preparation Products And Raw materials |
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