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| | (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester Basic information |
| Product Name: | (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester | | Synonyms: | (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester;Atorvastatin Impurity 111;(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid 1,1-DiMethylethyl Ester;Ats-7;[R-(R*,R*)]-tert-Butyl 6-cyano-3,5-dihydroxyhexanoate;tert-Butyl (3R,5R)-6-cyano-3,5-dihydroxyhexanoate;(3R,5R)-tert-butyl-6-cyano-3,5-dihydroxyhexanoate;Hexanoic acid, 6-cyano-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5R)- | | CAS: | 125971-93-9 | | MF: | C11H19NO4 | | MW: | 229.27 | | EINECS: | | | Product Categories: | Aliphatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 125971-93-9.mol |  |
| | (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester Chemical Properties |
| Boiling point | 410.2±45.0 °C(Predicted) | | density | 1.130±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.49±0.20(Predicted) | | color | Yellow to Orange to Pale Yellow |
| | (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester Usage And Synthesis |
| Chemical Properties | Yellow to Orange Oil | | Uses | Intermediate in the production of Atorvastatin. |
| | (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester Preparation Products And Raw materials |
| Raw materials | BUTANOIC ACID, 4-CYANO-3-HYDROXY-, METHYL ESTER, (3R)--->Hexanoic acid, 6-cyano-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester-->141942-82-7-->(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate-->Ethyl (R)-(-)-4-cyano-3-hydroxybutyate-->tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate-->(5R)-6-Cyano-5-hydroxy-3-oxo-hexanoic Acid tert-Butyl Ester-->Methoxydiethylborane-->Sodium cyanide-->sodium:cyanide | | Preparation Products | (3S,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester |
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