|
| | Gestodene Basic information |
| Product Name: | Gestodene | | Synonyms: | (8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one;17-alpha-Ethynyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one;18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha);(17R)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one;15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-6,12-dien-5-one;Gestodene Methyl analogue: 17alpha-(1-Propyn-1-yl)-17a-hydroxy-18-Methyl-4,15-estradien-3-one;(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one;(8R,9S,10R,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,7,8,10,11,12,13,17-octahydro-2H-cyclopenta[a]phenanthren-3(6H,9H,14H)-one | | CAS: | 60282-87-3 | | MF: | C21H26O2 | | MW: | 310.43 | | EINECS: | 262-145-8 | | Product Categories: | Steroid and Hormone;Hormone Drugs;Miscellaneous Biochemicals;Hormone;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 60282-87-3.mol |  |
| | Gestodene Chemical Properties |
| Melting point | 190-192°C | | Boiling point | 462.7±45.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO: >20mg/mL | | pka | 12.16±0.40(Predicted) | | form | powder | | color | white to off-white | | optical activity | [α]/D -175 to -195° (DCM) | | λmax | 240nm(MeOH)(lit.) | | Merck | 14,4413 | | InChIKey | SIGSPDASOTUPFS-XUDSTZEESA-N | | CAS DataBase Reference | 60282-87-3(CAS DataBase Reference) |
| | Gestodene Usage And Synthesis |
| Description | Gestodene is a progestogen, recently launched in combination with ethinyl estradiol as an
oral contraceptive.Gestodene is a steroid. It has a role as an estrogen.Gestodene, one of
three new gonane progestins, is the most potent on a per weight basis in
regard to progestational effects and has little or no estrogenic
effect. In in vivo animal studies, gestodene also has less androgenic
activity compared with progestins found in older combination oral
contraceptive formulations. | | Chemical Properties | White Crystalline Solid | | Originator | Schering AG (W. Germany) | | Uses | Estrogens and progestins are female hormones. They are produced by the body and are necessary for the normal sexual development of the female and for the regulation of the menstrual cycle during the childbearing years. Gestodene is a progestogen hormonal | | Uses | Orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive. | | Uses | Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive. | | Definition | ChEBI: Gestodene is a steroid. It has a role as an estrogen. | | Brand name | Femodene |
| | Gestodene Preparation Products And Raw materials |
|
