N-Boc-2-piperidinecarboxylic acid

N-Boc-2-piperidinecarboxylic acid Basic information

Product Name:	N-Boc-2-piperidinecarboxylic acid
Synonyms:	N-ALPHA-T-BUTOXYCARBONYL-DL-HOMOPROLINE;N-ALPHA-T-BUTOXYCARBONYL-DL-PIPECOLIC ACID;N-BOC-PIPERIDINE-2-CARBOXYLIC ACID;N-BOC-2-PIPERIDINECARBOXYLIC ACID;N-BOC-DL-PIPECOLINIC ACID;N-TERT-BUTOXYCARBONYL-2-PIPERIDINECARBOXYLIC ACID;RAC 1-TERT-BUTOXYCARBONYL-PIPERIDINE-2-CARBOXYLIC ACID;RAC 1-BOC-PIPERIDINE-2-CARBOXYLIC ACID
CAS:	98303-20-9
MF:	C11H19NO4
MW:	229.27
EINECS:	628-632-8
Product Categories:	Amino Acids and Derivatives;Carboxylic Acids;Pyrans, Piperidines &Piperazines;Piperidine;Carboxylic Acids;Pyrans, Piperidines & Piperazines
Mol File:	98303-20-9.mol

N-Boc-2-piperidinecarboxylic acid Chemical Properties

Melting point	130-133 °C (lit.)
Boiling point	353.2±35.0 °C(Predicted)
density	1.164±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	4.03±0.20(Predicted)
form	Crystalline Powder
color	White
BRN	480022
InChIKey	JQAOHGMPAAWWQO-UHFFFAOYSA-N
CAS DataBase Reference	98303-20-9(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

N-Boc-2-piperidinecarboxylic acid Usage And Synthesis

Chemical Properties	White crystalline powder
Uses	DL-Boc-pipecolic acid is the protected form of Pipecolic acid (P479760). Pipecolic acid is an intemediary metabolite of L-Lysine (L468895). Its accumulation in the body is characteristic of peroxisomal disorders in infants (such as Zeilweiger syndrome). Pipecolic acid is also used as a catalyst in asymmetric Mannich reactions.

N-Boc-2-piperidinecarboxylic acid Preparation Products And Raw materials

Raw materials	N-Boc-DL-Pipecolic acid methyl ester-->DL-Pipecolinic acid
Preparation Products	1-Methyl-2-piperidinemethanol-->N-Boc-piperidine-2-methanol-->2,6-PIPECOLINOXYLIDIDE HYDROCHLORIDE

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