3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Basic information
Product Name:3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-
Synonyms:exo-3-ami-8-benzyl-8-azabicyclo[3.2.1]octane;3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-;8-Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine;Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine;exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane;8-Azabicyclo[3.2.1]octan-3-amine,8-(phenylmethyl)-, (3-exo)-;8-Benzyl-8-azabicyclo[3.2.1]octane-3-exo-amino;8-benzyl-8-azabicyclo[3.2.1]octan-1-aMine
CAS:76272-36-1
MF:C14H20N2
MW:216.33
EINECS:
Product Categories:Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:76272-36-1.mol
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Structure
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Chemical Properties
Boiling point 110-115 °C(Press: 0.05 Torr)
density 1.082±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
pka10.23±0.20(Predicted)
form Oil
color Clear Light yellow to Beige
Safety Information
MSDS Information
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Usage And Synthesis
UsesIntermediate in the preparation of CCR5 receptor antagonists, antibacterial agents and dopamine antagonists
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Preparation Products And Raw materials
Raw materials8-Azabicyclo[3.2.1]octan-3-one, 8-methyl-, oxime-->8-BENZYL-1AH,5AH-NORTROPAN-3-ONE OXIME-->N-Benzyltropinone-->1,3-Acetonedicarboxylic acid-->Nortropan-3-one-->Tropinone-->Benzylamine
Preparation Productsexo-3-Boc-aminotropane
2-Amino-N-(8-benzyl-3-beta-nortropanyl)-4-ethoxy-5-pyrimidinecarboxami de maleate 2-Amino-N-(8-(o-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide Benzamide, 4-amino-5-bromo-N-(8-((4-ethylphenyl)methyl)-8-azabicyclo(3 .2.1)oct-3-yl)-2-methoxy-, exo- 5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-2-ethyl-4-met hoxy- 2-Amino-4-methoxy-N-(8-(o-methylbenzyl)-3-beta-nortropanyl)-5-pyrimidi necarboxamide 5-Pyrimidinecarboxamide, 2-amino-N-(8-(p-fluorobenzyl)-3-beta-nortropa nyl)-4-methoxy-, monomaleate 2-Amino-N-(8-(o-fluorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide 5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-4-ethoxy-2-et hyl- 2-Amino-4-methoxy-N-(8-(p-methylbenzyl)-3-beta-nortropanyl)-5-pyrimidi necarboxamide 5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-2-(dimethylam ino)-4-ethoxy-, monomaleate 2-Amino-N-(8-(p-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide 5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2 .1)oct-3-yl)-, exo- 2-Amino-N-(8-(m-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide 5-Pyrimidinecarboxamide, 2-amino-N-(8-benzyl-3-beta-nortropanyl)-4-met hoxy- Benzamide, 4-amino-5-bromo-N-(8-((3,4-dichlorophenyl)methyl)-8-azabicy clo(3.2.1)oct-3-yl)-2-methoxy-, exo- exo-5-Bromo-2,3-dimethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3 -yl)benzamide 2-Amino-4-methoxy-N-(8-(p-nitrobenzyl)-3-beta-nortropanyl)-5-pyrimidin ecarboxamide maleate 5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-2-(dimethylam ino)-4-methoxy-, monomaleate

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