Isocorynoxeine

Isocorynoxeine Basic information
Product Name:Isocorynoxeine
Synonyms:Isocorynoxeine;(16E,20α)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester;(alphaE,1'S,6'R,7'S,8'aS)-6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-alpha-(methoxymethylene)-2-oxospiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid methyl ester;Isocorynoxeine, BR;Isocorynoxeine (7-Isocorynoxeine);Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'S,6'R,7'S,8'aS)-;Isocorynoxeine USP/EP/BP;methyl (E)-2-[(3S,6'R,7'S,8'aS)-6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
CAS:51014-29-0
MF:C22H26N2O4
MW:382.46
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:51014-29-0.mol
Isocorynoxeine Structure
Isocorynoxeine Chemical Properties
Boiling point 562.7±50.0 °C(Predicted)
density 1.25
solubility DMSO : 50 mg/mL (130.74 mM; Need ultrasonic)
form Powder
pka13.54±0.60(Predicted)
Safety Information
MSDS Information
Isocorynoxeine Usage And Synthesis
DescriptionThe leaves of Mitragyna rotundlfolia grown in Burma have recently been found to contain this alkaloid. This is the first reported occurrence of the base in nature. The structure has been established from spectroscopic investigations.
Uses7-Isocorynoxeine is a bioactive oxindole alkaloid in the Uncaria species. Displays wide array of beneficial cardiovascular and cardiocerebral vascular system effects.
target5-HT2A receptor | NO
ReferencesHoughton, Shellard, Planta Med., 26, 104 (1974)
Isocorynoxeine Preparation Products And Raw materials
Nicotinic acid Leonurine hydrochloride NARIRUTIN Polygalacic acid Ginkgolide A ISOGINKGETIN Alisol B acetate ISOLIQUIRITIN demethylwedelolactone Isochlorogenic Acid B 4-[(2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-2-methoxyphenol Isofraxidin Isochlorogenic acid A Cryptochlorogenic acid polygalaxanthone III Isoalantolactone 3,5-Diisopropylbenzene hydroperoxide Rhynchophylline

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