euscaphic acid

euscaphic acid Basic information
Product Name:euscaphic acid
Synonyms:euscaphic acid;Acuminatic acid;Euscapic acid;Euscophic acid;Jacarandic acid;euscaphicaci;Urs-12-en-28-oic acid,2,3,19-trihydroxy-, (2a,3a)-;Urs-12-en-28-oic acid, 2,3,19-trihydroxy-, (2α,3α)-
CAS:53155-25-2
MF:C30H48O5
MW:488.7
EINECS:200-258-5
Product Categories:Triterpenoids
Mol File:53155-25-2.mol
euscaphic acid Structure
euscaphic acid Chemical Properties
Melting point 262-264 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point 602.7±55.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Methanol (Slightly), Pyridine (Slightly)
pka4.47±0.70(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
euscaphic acid Usage And Synthesis
UsesEuscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses.
DefinitionChEBI: Euscaphic acid is a pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 19 respectively (the 2alpha,3alpha-stereoisomer). It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid and a triol. It derives from a hydride of an ursane.
targetLDL | NO | PGE | TNF-α | NOS | COX | NF-kB | JNK | ERK | p38MAPK | Calcium Channel | Sodium Channel | ATPase | Potassium Channel | IkB | IKK
euscaphic acid Preparation Products And Raw materials
Poricoic acid A(F) dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone Betulinic acid Pachymic acid Madecassoside Carboxyatractyloside D(-)-Tartaric acid Madecassic acid roburic acid C10465 ALLEOSIDE A RHOIFOLIN Terrestrosin D Terrestrosin K 3-Epiursolic acid Pygenic acid A euscaphic acid

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