2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)

2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) Basic information
Product Name:2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)
Synonyms:2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI);(S)-1-(2-hydroxyacetyl)pyrrolidine-2-carboxamide;1-glycoloyl-L-proline amide;Vildagliptin Impurity 22/(S)-1-(2-hydroxyacetyl)pyrrolidine-2-carboxamide;Vildagliptin Impurity 48;1-Glycoloyl-L-prolinamide;(S)-1-(Hydroxyacetyl)-2-pyrrolidinecarboxamide;Vildagliptin Impurity -01 VN-01
CAS:96166-39-1
MF:C7H12N2O3
MW:172.18
EINECS:
Product Categories:PYRROLE
Mol File:96166-39-1.mol
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) Structure
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) Chemical Properties
Boiling point 484.2±45.0 °C(Predicted)
density 1.356±0.06 g/cm3(Predicted)
pka13.58±0.10(Predicted)
Safety Information
MSDS Information
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) Usage And Synthesis
Uses(S)-1-(Hydroxyacetyl)-2-pyrrolidinecarboxamide, is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) Preparation Products And Raw materials
Raw materialsL-Prolinamide-->CHLOROAC-PRO-OH-->(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide-->L-Proline
2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI) Dichloroacetyl chloride Vildagliptin Impurity 25 Vildagliptin Impurity 6 1-Adamantanol Vildagliptin IMpurity 2 (Mixture of DiastereoMers) N-acetic acid-1-aMino-3-adaMantanol Vildagliptin Related Compound C Vildagliptin Impurity 19 Amantadine 1,3,5,7-tetrahydroxyadamantane L-Proline, 4-chloro-, trans- Vildagliptin Carboxylic Acid Vildagliptin iMpurity A-F 3-Amino-1-hydroxyadamantane Cyanuric acid cis-cyclo(Pro-Pro) Vildagliptin Impurity 35

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