2,4-Dichlorothieno[3,2-d]pyrimidine

2,4-Dichlorothieno[3,2-d]pyrimidine Basic information
Product Name:2,4-Dichlorothieno[3,2-d]pyrimidine
Synonyms:Thieno[3,2-d]pyrimidine, 2,4-dichloro-;2,4-Dichlorothiopheno[3,2-d]pyrimidine;2,4-dichlorothieno[3,2-d]pyrimidine ,97%;2,4-dichlorothieno[3,2-d]...;4-dichlorothieno[3;2,4-dichlorothieno;2,4-dichlorothieno[3,2-d]pgriMidine;2,4-Dichlorothieno[3,2-d]pyrimidine
CAS:16234-14-3
MF:C6H2Cl2N2S
MW:205.06
EINECS:695-110-4
Product Categories:Heterocycle-Pyrimidine series;API intermediates;Heterocycles;CHIRAL CHEMICALS
Mol File:16234-14-3.mol
2,4-Dichlorothieno[3,2-d]pyrimidine Structure
2,4-Dichlorothieno[3,2-d]pyrimidine Chemical Properties
Melting point 136.0 to 140.0 °C
Boiling point 274.8±22.0 °C(Predicted)
density 1.662±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder to crystal
pka-0.72±0.40(Predicted)
color White to Almost white
InChIInChI=1S/C6H2Cl2N2S/c7-5-4-3(1-2-11-4)9-6(8)10-5/h1-2H
InChIKeyAQECFYPZMBRCIA-UHFFFAOYSA-N
SMILESC1(Cl)=NC(Cl)=C2SC=CC2=N1
Safety Information
Safety Statements 24/25
RIDADR UN2811
HazardClass IRRITANT
HS Code 29335990
MSDS Information
2,4-Dichlorothieno[3,2-d]pyrimidine Usage And Synthesis
Chemical Properties2,4-Dichlorothieno[3,2-d]pyrimidine is White solid
Uses2,4-Dichlorothieno[3,2-d]pyrimidine is used in the synthesis of PI3K inhibitor under noncryogenic conditions.
2,4-Dichlorothieno[3,2-d]pyrimidine Preparation Products And Raw materials
Raw materialsPhosphorus oxychloride-->Urea-->Methyl 3-amino-2-thiophenecarboxylate
Preparation ProductsOlmutinib-->2,4,7-Trichlorothieno[3,2-d]pyriMidine-->2-Chloro-N-methylthieno[3,2-d]pyrimidin-4-amine
Acetonitrile Glycidyl methacrylate Trifluoroacetic acid Acid chloride Phosphorus 2,4-Dichlorothieno[3,2-d]pyrimidine 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine 2,4-DICHLORO-6-METHYLTHIENO[3,2-D]PYRIMIDINE

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