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| | Isoliensinine Basic information |
| Product Name: | Isoliensinine | | Synonyms: | Isoliensinine;(+)-Isoliensinin;(1R)-1,2,3,4-Tetrahydro-1-[[4-hydroxy-3-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenyl]methyl]-6-methoxy-2-methyl-7-isoquinolinol;(1R)-1-[[4-hydroxy-3-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-hydroxy-3-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenyl]methyl]-6-methoxy-2-methyl-, (1R)-;Isoliensinine USP/EP/BP;(+)-Isoliensinine;(1R)-1-(4-hydroxy-3-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-m... | | CAS: | 6817-41-0 | | MF: | C37H42N2O6 | | MW: | 610.74 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 6817-41-0.mol |  |
| | Isoliensinine Chemical Properties |
| Melting point | 69-71℃ | | Boiling point | 723.1±60.0 °C(Predicted) | | density | 1.218 | | storage temp. | 2-8°C(protect from light) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 9.28±0.45(Predicted) | | form | powder | | color | White |
| | Isoliensinine Usage And Synthesis |
| Description | Tomita and his co-workers have obtained this bisisoquinoline alkaloid from the
embryo of the seeds of Nelumbo nucifera Gaertn. The base has [α]29D + 49.3°
(Me2CO) and - 43.3° (CHC13 ). The hydrochloride tetrahydrate forms colourless
crystals, m.p. l85-6°C (dry); the perchlorate monohydrate has m.p. 200-3°C
(dry); [α]22D - 70° (Me2CO) and the styphnate of the O,O-dimethyl ether, also
crystalline, has m.p. l33-5°C; [α]27D - 81.5° (Me2CO). Three methoxyl, two
hydroxyl and two methylimino groups are present. | | Uses | (+)-Isoliensinine is an alkaloid which displays activation of AMP-activated kinase and regulation of PPARγ receptors. | | Definition | ChEBI: Isoliensinine is a member of isoquinolines. | | References | Tomita et aI., Tetrahedron Lett., 2637,3374 (1964) |
| | Isoliensinine Preparation Products And Raw materials |
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