[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Basic information
Product Name:[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Synonyms:[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;Sulbactam Impurity 1;Tazobactam Acid Impurity 15;SULBACTAM IMPURITY 1 (6-ALPHA-BROMOPENICLLANIC ACID);Tazobactam Impurity 16;(2S,5β)-6β-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid;(2S-(2alpha,5alpha,6alpha))-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid;Einecs 246-028-9
CAS:24138-28-1
MF:C8H10BrNO3S
MW:280.14
EINECS:246-028-9
Product Categories:
Mol File:24138-28-1.mol
[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Structure
[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical Properties
Boiling point 462.6±45.0 °C(Predicted)
density 1.84±0.1 g/cm3(Predicted)
solubility Methanol
form Solid
pka2.43±0.50(Predicted)
color Brown
Stability:Hygroscopic, Light sensitive, Temperature sensitive
Safety Information
MSDS Information
[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Usage And Synthesis
Uses6α-Bromopenicillanic acid is an intermediate in the synthesis of Tazobactam Sodium Salt-13C2,15N1, which is the labelled analogue of Tazobactam Sodium Salt (T010100), which is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.
[2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Preparation Products And Raw materials
Raw materials(2S,5R,6S)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid-->6,6-DIBROMOPENICILLANIC ACID-->6-Aminopenicillanic acid
Preparation Productsbrobactam-->BROMOSULBACTAM-->(2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE] Benzophenone hydrazone Tazobactam Acid Impurity 16 Tazobactam Impurity B Tazobactam Impurity 5 Tazobactam Acid Impurity 14 Tazobactam Acid Impurity 12 Tazobactam Diphenylmethyl Ester (2S,5R)-3α-Chloromethyl-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid benzhydryl ester 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-bromo-3,3-dimethyl-7-oxo-, diphenylmethyl ester, 4-oxide, (2S,5R,6S)- 1,2,3-1H-Triazole tazobactam 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(chloromethyl)-3-methyl-7-oxo-, [2S-(2α,3β,5α)]- (9CI) Tazobactam Impurity 2 Tazobactam acid Phenol, 2-(diphenylmethyl)-5-methyl- Tazobactam Acid Impurity 17 2-aMino-3-Methyl-3-sulfino-4-(1H-1,2,3-triazol-1-yl)butyric acid

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