11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione

11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione Basic information
Product Name:11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione
Synonyms:11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione;11β,16α,17,21-Tetrahydroxypregn-4-ene-3,20-dione;Budesonide Impurity 10;Budesonide EP Impurity 10;16α-Hydroxycortisol;-Hydroxycortisol;Budesonide Impurity 54;Budesonide Impurity 41
CAS:1171-81-9
MF:C21H30O6
MW:378.4593
EINECS:214-627-4
Product Categories:
Mol File:1171-81-9.mol
11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione Structure
11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione Chemical Properties
Melting point >217°C (dec.)
Boiling point 587.1±50.0 °C(Predicted)
density 1.35±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (slightly), Methanol (Slightly, Heated)
pka11.94±0.70(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione Usage And Synthesis
Uses11β,16α,17,21-Tetrahydroxypregn-4-ene-3,20-dione is a metabolite of Hydroxycortisone (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione Preparation Products And Raw materials
16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers) 21-Dehydro Budesonide IMp. A (EP): 11β,16α,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione (16-Hydroxy- prednisolone) Budesonide Impurity 7 21-Acetoxy-11-oxo-16α,17α-propylMethylenedioxpregna-1,4-diene-3,20-dione (11β,16α)-21-(Acetyloxy)-11,16,17-trihydroxypregna-1,4,14-triene-3,20-dione Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-16,17-dihydroxy-, (9β,11β,16α)- Prednisone 17, 21-Diacetate Budesonide Impurity 11 Budesonide Impurity 18 16α,17,21-Trihydroxy-pregna-1,4-diene-3,11,20-trione Budesonide iMpurity 21-Acetoxy-11β-hydroxy-16α,17α-propylmethylenedioxpregna-1,4-diene-3,20-dione Budesonide Impurity 6 (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione 21-Dehydro-16α-hydroxy Prednisolone 1,2-Dehydrobudesonide 2,4,6-tripropyl-1,3,5-trioxane

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