DESMETHYL MIRTAZAPINE

DESMETHYL MIRTAZAPINE Basic information
Product Name:DESMETHYL MIRTAZAPINE
Synonyms:Mirtazapine EP Impurity D (base));Desmethyl Mirtazapine Discontinued See: D292074;N-Desmethylmirtazapine;Mirtazapine Related Compound A (15 mg) (1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine);1,2,3,4,10,14b-Hexahydro-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine N-DeMethylMirtazapine;N-DesMethyl Mirtazepine;Mirtazapine EP IMpurity D (USP RC A);Mirtazapine EP IMpurity D
CAS:61337-68-6
MF:C16H17N3
MW:251.33
EINECS:200-835-2
Product Categories:Heterocycles. Metabolites & Impurities;Metabolites & Impurities;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:61337-68-6.mol
DESMETHYL MIRTAZAPINE Structure
DESMETHYL MIRTAZAPINE Chemical Properties
Melting point >195?C (dec.)
Boiling point 456.1±33.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
Fp 2℃
storage temp. -20°C
solubility Methanol (Slightly), Water (Slightly)
pka9.00±0.20(Predicted)
form neat
BRN 3976057
Safety Information
Hazard Codes F,Xn
Risk Statements 11-20/21/22-36
Safety Statements 16-36/37
RIDADR UN 1648 3 / PGII
WGK Germany 2
HS Code 2933599550
MSDS Information
DESMETHYL MIRTAZAPINE Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA metabolite of Mirtazapine, a2-Adrenergic blocker.
UsesA metabolite of Mirtazapine, α2-adrenergic blocker.
DefinitionChEBI: N-demethylmirtazapine is a benzazepine metabolite resulting from demethylation of the antidpressant, mirtazapine. It has a role as a human xenobiotic metabolite, an alpha-adrenergic antagonist, an anxiolytic drug, a H1-receptor antagonist, a histamine antagonist and a serotonergic antagonist. It is a tetracyclic antidepressant and a benzazepine.
DESMETHYL MIRTAZAPINE Preparation Products And Raw materials
DesMethyl Mirtazapine Hydrochloride Mirtazapine 8-HYDROXY MIRTAZAPINE 2(RS)-4-Methyl-1-(3-Methylpyridin-2-yl)-2-phenylpiperazine 1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine (R)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-(4-methyl-3-phenylpiperazin-1-yl)nicotinaldehyde hydrochloride 1-(3-Cyanopyridyl-2)-2-Phenyl-4-Methylpyperazine 1-Oxo Mirtazapine (Mirtazapine Impurity C) 8-Hydroxy mirtazapine-d4 DESMETHYL MIRTAZAPINE MIRTAZAPINE-D4 Mirtazapine-d4 HCl Mirtazapine-D3 Mirtazapine DESMETHYL MIRTAZAPINE-D4 HCL DESMETHYL MIRTAZAPINE HCL

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