Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
MSDS Information
BENZOTRIPT Usage And Synthesis
Description
Benzotript (39544-74-6) antagonizes the interaction of cholecystokinin and related peptides with the cholecystokinin receptor.1 ?It has been reported to potentiate morphine analgesia via interaction with opioid receptors.2
Uses
Benzotript is an antiulcer drug that is a cholecystokinin receptor (CCK-2R) antagonist .
References
1) Hahne (1981), Proglumide and benzotript: Members of a different class of cholecystokinin receptor antagonists; Proc. Natl. Acad. Sci. USA. 78 6304
2) Gaudreau et al. (1990), Cholecystokinin antagonists proglumide, lorglumide and benzotript, but not L-364,718, interact with brain opioid binding sites; Neuropeptides 16 51