LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Basic information
Product Name:LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
Synonyms:2,5-dihydroxy-l-tyrosine;4,5-trihydroxyphenyl)-3-(l-alanin;6-oh-dopa;l-2,4,5-trihydroxyphenylalanine;l-6-hydroxydopa;l-hydroxydopa;LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE);(S)-α-Amino-3,4,6-trihydroxybenzenepropanoic acid
CAS:27244-64-0
MF:C9H11NO5
MW:213.19
EINECS:
Product Categories:Amino Acids & Derivatives, Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:27244-64-0.mol
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Structure
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Chemical Properties
Melting point >190°C (dec.)
Boiling point 515.2±38.0 °C(Predicted)
density 1.606±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated)
pka2.34±0.25(Predicted)
form neat
color Brown to Black
Stability:Air Sensitive, Hygroscopic
Safety Information
HS Code 2922504500
MSDS Information
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Usage And Synthesis
Uses6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
Uses6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
DefinitionChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6.
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Preparation Products And Raw materials
3,4-DIHYDROXYPHENYLACETONE D-DOPA Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol) L-Tyrosine L-DOPA-4'-Sulfate Levodopa (S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- 5,6-dihydroxy-1H-indole-2-carboxylic acid Albuterol Aldehyde 3-METHOXY-DL-TYROSINE 2,3-Dihydroxy-L-Phenylalanine 3-O-Methylcarbidopa 3,4-Dimethoxy-L-phenylalanine 3-METHOXY-L-TYROSINE 2,3-Dihydroxy-DL-Phenylalanine Levosimendan Impurity 14

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