2,3-Dihydroxybenzoic acid

2,3-Dihydroxybenzoic acid Basic information
Product Name:2,3-Dihydroxybenzoic acid
Synonyms:2,3-dihydroxybenzoate;3-hydroxysalicylicacid;catecholcarboxylicacid;DOBK;Pyrocatechuic acid;DIHYDROXYBENZOIC ACID, 2,3-;CATECHOL-3-CARBOXYLIC ACID;2,3-DIHDROXYBENZOIC ACID
CAS:303-38-8
MF:C7H6O4
MW:154.12
EINECS:206-139-5
Product Categories:Building Blocks;Carbonyl Compounds;C7;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;BenzoicAcidDerivative;Benzoic acid;Organic acids;API intermediates;Aromatics Compounds;Carbonyl Compounds;Carboxylic Acids;Acids and Derivatives;Alcohols and Derivatives;Aromatics
Mol File:303-38-8.mol
2,3-Dihydroxybenzoic acid Structure
2,3-Dihydroxybenzoic acid Chemical Properties
Melting point 204-206 °C (lit.)
Boiling point 95-96/0.5mm
density 1,542 g/cm3
refractive index 1.6400 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility methanol: soluble50mg/mL, clear to faintly hazy, orange
pkapK1:2.98;pK2:10.14 (30°C)
form Crystalline Powder
color Beige to brown or pinkish-gray
Water Solubility Soluble in water, methanol and dimethyl sulfoxide.
BRN 2209117
InChIKeyGLDQAMYCGOIJDV-UHFFFAOYSA-N
LogP1.200
CAS DataBase Reference303-38-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoic acid, 2,3-dihydroxy-(303-38-8)
EPA Substance Registry System2,3-Dihydroxybenzoic acid (303-38-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 2
RTECS DG8576490
Hazard Note Irritant
HS Code 29182900
MSDS Information
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2,3-Dihydroxybenzoic acid Usage And Synthesis
Chemical PropertiesPale Brownish to Red Brownish Crystalline Powder
Uses2,3-Dihydroxybenzoic Acid is a selected phenol as MMP (Matrix Metalloproteinase) inhibitor.
Uses2,3-Dihydroxybenzoic acid was used to study the complexes of manganese with aliphatic and aromatic polyhydroxy ligands in basic media by electrochemical, spectrophotometric and magnetic methods. It was used in isolation of new siderophore named vulnibactin from low iron cultures of Vibrio vulnificus, a human pathogen. It was used as cocrystal former to study the influence of position isomerism on the co-crystals formation and physicochemical properties of piracetam.
DefinitionChEBI: A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Biochem/physiol Actions2,3-Dihydroxybenzoic acid was found to be orally effective iron-chelating drug in hypertransfused rat model. It is monocatechol siderophore produced by Brucella abortus.
2,3-Dihydroxybenzoic acid Preparation Products And Raw materials
Preparation ProductsLY 294002 HYDROCHLORIDE-->1,3-BENZODIOXOLE-4-CARBOXYLIC ACID-->1,3-Benzodioxole-4-carbonyl chloride (9CI)-->2,3-Dibenzyl-5-broMobenzoic Acid Methyl Ester
Methylparaben 4-Hydroxybenzoic acid Salicylic acid methyl 2,3-dihydroxybenzoate 2'-Hydroxy-3-phenylpropiophenone Protocatechuic acid 2,3-Dihydroxybenzoic acid METHYL 2,3-DIMETHOXY BENZOATE 2,4-DIHYDROXYBENZOIC ACID 4-METHOXY-2,3-DIHYDROXYBENZOIC ACID Butylparaben 2,5-DIHYDROXYBENZOIC ACID Isopropylparaben 2,3-Dimethoxybenzoic acid 2,3,4-Trihydroxybenzoic acid phosphoric acid 2,6-DIHYDROXYBENZOIC ACID 5-CARBOXYVANILLIC ACID

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