ChemicalBook Product Catalog API Synthetic Anti-infective Drugs Sulfonamides and synergist PHTHALYLSULFACETAMIDE

PHTHALYLSULFACETAMIDE

PHTHALYLSULFACETAMIDE Basic information
Product Name:PHTHALYLSULFACETAMIDE
Synonyms:LABOTEST-BB LT00438470;4'-(ACETYLSULFAMOYL)PHTHALANILIC ACID;2-([[4-([ACETYLAMINO]SULFONYL)PHENYL]AMINO]CARBONYL)BENZOIC ACID;N-(4-ACETYLSULFAMOYL-PHENYL)-PHTHALAMIC ACID;N1-ACETYL-N4-PHTHALYLSULFANILAMIDE;PHTHALYLSULFACETAMIDE;2-((4-[(Acetylamino)sulfonyl]anilino)carbonyl)benzoic acid;2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]-benzoicaci
CAS:131-69-1
MF:C16H14N2O6S
MW:362.36
EINECS:205-035-7
Product Categories:TALSIGEL
Mol File:131-69-1.mol
PHTHALYLSULFACETAMIDE Structure
PHTHALYLSULFACETAMIDE Chemical Properties
Melting point 196°
storage temp. Sealed in dry,Room Temperature
solubility DMSO : ≥ 50 mg/mL (137.98 mM)
form neat
EPA Substance Registry SystemBenzoic acid, 2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]- (131-69-1)
Safety Information
RIDADR 3249
WGK Germany 3
HazardClass 6.1(b)
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
PHTHALYLSULFACETAMIDE Usage And Synthesis
Usesantibacterial
DefinitionChEBI: Phthalylsulfacetamide is a member of benzamides.
Brand nameTalsigel (Bristol-Myers Squibb); Thalamyd (Schering) [Name previously used: Phthalylsulphacetamide.].
Purification MethodsIt is prepared by hydrolysis of N-acetamidosulfophenylpthalimide by boiling for 3hours in 15% aqueous KOH followed by treatment with Norit, filtration and acidification with AcOH. Crystallise the phthalamide from hot H2O or EtOH [Jain et al. J Indian Chem Soc 24 174 1947]. Itis antibacterial.[Beilstein 14 III 2073.]
PHTHALYLSULFACETAMIDE Preparation Products And Raw materials
Sulfadiazine [2-(aminomethyl)phenyl]methanol 4-AMINO-N-ETHYL-BENZENESULFONAMIDE PHTHALAMIC ACID N,N'-DIACETYLSULFANILAMIDE PHTHALYLSULFACETAMIDE Benzoic acid, 2-(aminomethyl)- (9CI) Sulfacetamide PHTHALANILLIC ACID benzylsulfamide 4-AMINO-N-METHYL-BENZENESULFONAMIDE 4-Acetamidothiophenol 2-METHYLBENZANILIDE 4-ETHYLAMINO-BENZENESULFONAMIDE 4-Acetamidobenzenesulfonamide 1,9-Pyrazoloanthrone o-(hydroxymethyl)benzamide -EthylbenzenesulfonaMide
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