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| | 2',3'-Dideoxythymidine Basic information |
| Product Name: | 2',3'-Dideoxythymidine | | Synonyms: | 3′-Deoxythymidine(DDT);3'-Deoxy-D-thymidine;3''-DESOXYTHYMIDINE;3''-DEOXYTHYMIDINE (2'', 3''-DIDEOXYTHYMIDINE);2μ,3μ-Dideoxythymidine, DDT;1-(2,3-Dideoxy-β-D-ribofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione;1-[5β-(Hydroxymethyl)tetrahydrofuran-2β-yl]-5-methyluracil;Dideoxythymidine | | CAS: | 3416-05-5 | | MF: | C10H14N2O4 | | MW: | 226.23 | | EINECS: | 2017-001-1 | | Product Categories: | Heterocycle-Pyrimidine series;pyrimidine | | Mol File: | 3416-05-5.mol |  |
| | 2',3'-Dideoxythymidine Chemical Properties |
| Melting point | 155-156 °C(lit.) | | alpha | 20 º (C=0.6 IN H2O) | | density | 1.332±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml | | form | Powder | | pka | 9.55±0.10(Predicted) | | color | White to Pale Yellow | | optical activity | [α]19/D +20.0°, c = 0.6 in H2O | | BRN | 21884 | | InChIKey | XKKCQTLDIPIRQD-JGVFFNPUSA-N | | CAS DataBase Reference | 3416-05-5(CAS DataBase Reference) |
| | 2',3'-Dideoxythymidine Usage And Synthesis |
| Uses | 3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor. | | Uses | Research tool for antiviral and anticancer studies. | | Purification Methods | 3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.] |
| | 2',3'-Dideoxythymidine Preparation Products And Raw materials |
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