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| | 2-Pyrazinecarboxylic acid Basic information |
| Product Name: | 2-Pyrazinecarboxylic acid | | Synonyms: | 2-PYRAZINECARBOXYLIC ACID;AKOS BBS-00003784;Pyrazinecarboxylice acid;SodiumStearlyFumarate;Pyrazinecarboxylicacid,99%;1,4-Diazine-2-carboxylic acid;2-Pyrazinecarboxylic aci;1,4-Diazinecarboxylic acid | | CAS: | 98-97-5 | | MF: | C5H4N2O2 | | MW: | 124.1 | | EINECS: | 202-718-1 | | Product Categories: | Other APIs;Aromatics, Heterocycles, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Pyrazine;Organic acids;Pyrazinecarboxylic Acid & Derivatives;Pyrazines;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Heterocyclic Building Blocks;Fluorobenzene;Intermediates;bc0001;98-97-5 | | Mol File: | 98-97-5.mol |  |
| | 2-Pyrazinecarboxylic acid Chemical Properties |
| Melting point | 222-225 °C (dec.)(lit.) | | Boiling point | 230.85°C (rough estimate) | | density | 1.4317 (rough estimate) | | vapor pressure | 0.011Pa at 25℃ | | refractive index | 1.4800 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | form | Crystalline Powder | | pka | pK (25°) 2.92 | | color | White to off-white | | Water Solubility | SOLUBLE IN COLD WATER | | Merck | 14,8970 | | BRN | 112305 | | InChIKey | NIPZZXUFJPQHNH-UHFFFAOYSA-N | | LogP | -0.18 | | CAS DataBase Reference | 98-97-5(CAS DataBase Reference) | | NIST Chemistry Reference | Pyrazinoic acid(98-97-5) |
| | 2-Pyrazinecarboxylic acid Usage And Synthesis |
| Chemical Properties | WHITE TO OFF-WHITE CRYSTALLINE POWDER | | Uses | Labelled analogue of Pyrazinecarboxylic Acid, a very potent urate retaining drug. Pyrazinecarboxylic Acid is a metabolite of the antibacterial agent Pyrazinamide (P840600). | | Uses | Pyrazinecarboxylic Acid is a very potent urate retaining drug. Pyrazinecarboxylic Acid is a metabolite of the antibacterial agent Pyrazinamide (P840600). | | Definition | ChEBI: The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 40, p. 1187, 1975 DOI: 10.1021/jo00896a050 | | Flammability and Explosibility | Notclassified | | Purification Methods | It crystallises from water. The methyl ester has m 62o (from pet ether). [Sauville & Spoerri J Am Chem Soc 63 3153 1941, Beilstein 25 III/IV 771.] |
| | 2-Pyrazinecarboxylic acid Preparation Products And Raw materials |
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