ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards NZWJKTHFNLHUJO-NWZSJJIMSA-N

NZWJKTHFNLHUJO-NWZSJJIMSA-N

NZWJKTHFNLHUJO-NWZSJJIMSA-N Basic information
Product Name:NZWJKTHFNLHUJO-NWZSJJIMSA-N
Synonyms:NZWJKTHFNLHUJO-NWZSJJIMSA-N;Rosuvastatin 2,3-Anhydro Acid Calcium Salt;((S,2Z,6E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl sulfonamido)pyrimidin-5-yl)-5-hydroxyhepta-2,6-dienoate) calcium(II);Rosuvastatin calcium-10;2,6-Heptadienoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-, (2Z,5S,6E)-;2Z,Dehydro Rosuvastatin;2,3-Anhydro Rosuvastatin Calcium Salt/ Rosuvastatin 2,6-Diene Impurity;Rosuvastatin EP Impurity K (2Z-isomer)
CAS:1422954-12-8
MF:C22H26FN3O5S
MW:463.52
EINECS:
Product Categories:
Mol File:1422954-12-8.mol
NZWJKTHFNLHUJO-NWZSJJIMSA-N Structure
NZWJKTHFNLHUJO-NWZSJJIMSA-N Chemical Properties
Boiling point 717.9±70.0 °C(Predicted)
density 1.333±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka4.30±0.25(Predicted)
color White to Off-White
Stability:Hygroscopic, Light Sensitive
Safety Information
MSDS Information
NZWJKTHFNLHUJO-NWZSJJIMSA-N Usage And Synthesis
UsesDehydro Rosuvastatin is an impurity of Rosuvastatin (R700500) which is a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
NZWJKTHFNLHUJO-NWZSJJIMSA-N Preparation Products And Raw materials
Desfluoro Rosuvastatin Sodium Salt Rosuvastatin Rosuvastatin Calcium Salt Rosuvastatin ethyl ester N-Desmethyl Rosuvastatin Lactone N-[(6R)-8-Fluoro-5,6-dihydro-4-(1-Methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-MethylMethanesulfonaMide (3R,5S)-5-((R)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-hydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate calcium(II) tert-Butyl rosuvastatin tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate (3R,5R)-Rosuvastatin Lactone Rosuvastatin Rosuvastatin methyl ester tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid Rosuvastatin Impurity 24(Sodium Salt) Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester) (3R,5R)-Rosuvastatin TRIS(4-METHYLPHENYL)PHOSPHINE OXIDE
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