trans-Ferulic acid

trans-Ferulic acid Basic information
Product Name:trans-Ferulic acid
Synonyms:(E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid;(e)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoicacid;(e)-ferulicacid;3-(4-Hydroxy-3-methoxyphenyl)propenoic acid;Cinnamic acid, 4-hydroxy-3-methoxy-, (E)-;Cinnamic acid, 4-hydroxy-3-methoxy-, trans-;Ferulic acid, trans-;trans-cinnamicaci
CAS:537-98-4
MF:C10H10O4
MW:194.18
EINECS:208-679-7
Product Categories:Cinnamic acid;Antioxidant;Biochemistry
Mol File:537-98-4.mol
trans-Ferulic acid Structure
trans-Ferulic acid Chemical Properties
Melting point 168-172 °C(lit.)
Boiling point 250.62°C (rough estimate)
density 1.316(20.0000℃)
refractive index 1.5030 (estimate)
Fp 150℃
storage temp. Store below +30°C.
solubility DMSO (Slightly), Methanol (Slightly)
form powder
pka4.58±0.10(Predicted)
color slightly yellow
Water Solubility Soluble in alcohol and hot water.
Merck 14,4062
BRN 1371483
Stability:Stable. Incompatible with strong oxidizing agents.
LogP1.641 (est)
CAS DataBase Reference537-98-4(CAS DataBase Reference)
NIST Chemistry Reference2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (e)-(537-98-4)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS UD3365500
TSCA Yes
HS Code 29189900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
trans-Ferulic acid Usage And Synthesis
Chemical Propertiessolid
UsesThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Usestrans-Ferulic acid was used for esterification of methacrylated dextran. It was also used to study the effect of oral administration of trans-ferulic acid to c57BL mice on ethanol-induced liver injury. Furthermore, it has been used in the synthesis of new biocompatible antioxidant polymers linking trans-ferulic acid.
DefinitionChEBI: Ferulic acid is a ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. It has a role as an antioxidant, a MALDI matrix material, a plant metabolite, an anti-inflammatory agent, an apoptosis inhibitor and a cardioprotective agent. It is a conjugate acid of a ferulate.
Biochem/physiol ActionsHydroxycinnamic acid found in plant-based foods. Antioxidant.
Purification MethodsCrystallise ferulic acid from H2O. [Beilstein 10 H 436, 10 IV 1776.]
trans-Ferulic acid Preparation Products And Raw materials
Raw materialsHydrochloric acid-->Pyridine-->Malonic acid-->Vanillin
3,4-Dimethoxycinnamonitrile trans-Ferulic acid N-BUTYL CINNAMATE 4-Methoxyphenylacetic acid m-Anisyl alcohol Methyl cinnamate (Trifluoromethoxy)benzene p-Coumaric acid 3-(METHOXYMETHOXY)BENZALDEHYDE trans,trans-2,4-Undecadienal trans-Cinnamic acid HYDROXYCINNAMIC ACID 4-Methoxycinnamic acid 3-Methoxycinnamic acid 4-Hydroxycinnamic acid CHLOROPHOSPHONAZO III o-Anisaldehyde TRANS-FERULIC ACID, ISOPROPYL ESTER

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