DE-7

DE-7 Basic information
Product Name:DE-7
Synonyms:DE-7;(R)-2-chloro-1-{(2-methyloxiran-2-yl)methyl}-4-nitro-1H-imidazole;2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole;Dilamanid intermediate;1H-Imidazole, 2-chloro-1-[[(2R)-2-methyl-2-oxiranyl]methyl]-4-nitro-
CAS:681490-93-7
MF:C7H8ClN3O3
MW:217.61
EINECS:
Product Categories:
Mol File:681490-93-7.mol
DE-7 Structure
DE-7 Chemical Properties
Melting point 72-73 °C
Boiling point 393.9±38.0 °C(Predicted)
density 1.68±0.1 g/cm3(Predicted)
solubility Chloroform, DCM
pka-2.55±0.60(Predicted)
form Solid
color Off-White
Safety Information
MSDS Information
DE-7 Usage And Synthesis
Uses2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

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