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phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate

phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Basic information
Product Name:phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate
Synonyms:phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate;Phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl)oxy-2-chlorophenyl)carbamate;Carbamic acid,[4-[[6-(aminocarbonyl)-7-methoxy-4-quinolinyl]oxy]-2-chlorophenyl]-,phenyl ester;CARBAMIC ACID,[4-[[6-(AMINOCARBONYL)-7-METHOXY-4-QUINOLINYL]OXY]-2-CHLOROPHENYL]-,PHENYL ESTER;;Lenvatinib Intermediates 2;Carbamic acid, N-[4-[[6-(aminocarbonyl)-7-methoxy-4-quinolinyl]oxy]-2-chlorophenyl]-, phenyl ester;Phenyloxy Descyclopropylamino Lenvatinib;Lenvatinib Impurity 14Q: What is Lenvatinib Impurity 14 Q: What is the CAS Number of Lenvatinib Impurity 14
CAS:417722-95-3
MF:C24H18ClN3O5
MW:463.87
EINECS:814-027-8
Product Categories:
Mol File:417722-95-3.mol
phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Structure
phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Chemical Properties
Boiling point 644.8±55.0 °C(Predicted)
density 1.418±0.06 g/cm3(Predicted)
pka11.16±0.70(Predicted)
Safety Information
MSDS Information
phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Usage And Synthesis
UsesPhenyloxy Descyclopropylamino Lenvatinib is an intermediate in the synthesis of Descyclopropyl Lenvatinib (D288150), a metabolite of Lenvatinib (L329400) which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Preparation Products And Raw materials
Lenvatinib Impurity g Lenvatinib Impurity 12 4-chloro-7-Methoxyquinoline-6-carboxaMide 7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxaMide Lenvatinib Impurity d Lenvatinib Impurity 2 4,4'-[Carbonylbis[imino(3-chloro-4,1-phenylene)oxy]]bis[7-methoxy-6-quinolinecarboxamide] 4-(4-amino-3-chlorophenoxy)-7-methoxyquinoline-6-carboxamide Descyclopropyl Lenvatinib 6-Quinolinecarboxamide, 4-hydroxy-7-methoxy- 6-Quinolinecarboxamide, 4-[(2-chloro-4-hydroxyphenyl)amino]-7-methoxy- 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(ethylamino)carbonyl]amino]phenoxy]-7-methoxy- Lenvatinib Impurity O Lenvatinib Impurity 5 6-Quinolinecarboxylic acid, 4-(4-amino-3-chlorophenoxy)-7-methoxy-, methyl ester Lenvatinib Impurity f Lenvatinib Impurity 8 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea
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