17- Phenyl Trinor Prostaglandin F2α Methyl Amide

17- Phenyl Trinor Prostaglandin F2α Methyl Amide Basic information
Product Name:17- Phenyl Trinor Prostaglandin F2α Methyl Amide
Synonyms:17- Phenyl Trinor Prostaglandin F2α Methyl Amide;17-phenyl trinor Prostaglandin F2.alpha. methyl amide;Bimatoprost Impurity 5;(~{Z})-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide;17- Phenyl Trinor Prostaglandin F2α Methyl Amide (10mg/mL in Ethanol);5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-, (5Z)-;Bimatoprost Impurity E;Bimatoprost Methyl Amide
CAS:155206-01-2
MF:C24H35NO4
MW:401.54
EINECS:
Product Categories:
Mol File:155206-01-2.mol
17- Phenyl Trinor Prostaglandin F2α Methyl Amide Structure
17- Phenyl Trinor Prostaglandin F2α Methyl Amide Chemical Properties
Boiling point 621.5±55.0 °C(Predicted)
density 1.159±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Ethanol
form Clear Colourless Solution
pka14.25±0.20(Predicted)
Safety Information
MSDS Information
17- Phenyl Trinor Prostaglandin F2α Methyl Amide Usage And Synthesis
Description17-phenyl trinor Prostaglandin F (17-phenyl trinor PGF) is a metabolically stable analog of PGF and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF. The ethyl amide of 17-phenyl trinor PGF bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
Uses17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is a stable analog of PGF2α and is a potent agonist of for the FP receptor. Analog of Bimatoprost (B386800), an antiglaucoma agent.
17- Phenyl Trinor Prostaglandin F2α Methyl Amide Preparation Products And Raw materials
(-)-Corey Lactone Diol (Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER Bimatoprost Impurity 18 BiMatoprost IMpurity III (5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromide Bimatoprost Impurity 13 (15R)-BiMatoprost LAT-NET Bimatoprost Impurity 21 (5E)-BiMatoprost Bimatoprost Impurity 14 Bimatoprost Impurity 2 (Mixture of Diastereomers) Dimethyl (2-oxo-4-phenylbutyl)phosphonate 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA Bimatoprost Impurity 22 Bimatoprost Impurity 15 CHEMPACIFIC 59929 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA

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