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| | Tubastatin-A Basic information |
| Product Name: | Tubastatin-A | | Synonyms: | N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;N-hydroxy-4-((2-methyl-2,3,4,5-tetrahydro-1H-indeno[1,2-c]pyridin-5-yl)methyl)benzamide;N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Tubastatin A;Tubastatin A BASE;Tubastatin A(free base);N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide;Tubastatin A (TubA, AG-CR1-3900);Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]- | | CAS: | 1252003-15-8 | | MF: | C20H21N3O2 | | MW: | 335.4 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1252003-15-8.mol |  |
| | Tubastatin-A Chemical Properties |
| density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | insoluble in EtOH; insoluble in H2O; ≥10.75 mg/mL in DMSO | | form | solid | | pka | 8.95±0.10(Predicted) |
| | Tubastatin-A Usage And Synthesis |
| Definition | ChEBI: A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminoca
bonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). | | target | HDAC6 |
| | Tubastatin-A Preparation Products And Raw materials |
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