Diphosphoryl chloride

Diphosphoryl chloride Basic information
Product Name:Diphosphoryl chloride
Synonyms:PYROPHOSPHORIC TETRACHLORIDE;PYROPHOSPHORYL CHLORIDE;PHOSPHORODICHLORIDIC ANHYDRIDE;DIPHOSPHORYL CHLORIDE;DIPHOSPHORIC TETRACHLORIDE;Dichlorophosphinoyloxydichlorophosphine oxide;Diphosphoric tetrachloride, Pyrophosphoric tetrachloride, Pyrophosphoryl chloride;diphosphoryl tetrachloride
CAS:13498-14-1
MF:Cl4O3P2
MW:251.76
EINECS:236-824-4
Product Categories:API;Pharmaceutical Intermediates;Phosphorylation;Synthetic Organic Chemistry
Mol File:13498-14-1.mol
Diphosphoryl chloride Structure
Diphosphoryl chloride Chemical Properties
Melting point <-50°C
Boiling point 90 °C12 mm Hg(lit.)
density 1.82 g/mL at 25 °C(lit.)
refractive index n20/D 1.476
Fp 101°C/10mm
storage temp. −20°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Liquid
color Colorless to pale yellow
Specific Gravity1.82
Water Solubility Reacts violently with waterMiscible with most organic solvents.
Sensitive Air & Moisture Sensitive
InChIKeyCNTIXUGILVWVHR-UHFFFAOYSA-N
CAS DataBase Reference13498-14-1(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 14-34
Safety Statements 26-36/37/39-45-60-30-23-20-8
RIDADR UN 3264 8/PG 2
WGK Germany 3
10-21
HazardClass 8
PackingGroup II
HS Code 28121049
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Diphosphoryl chloride Usage And Synthesis
Chemical PropertiesColorless liquid
UsesPyrophosphoryl chloride serves as a reductive chlorination reagent used in the synthesis of quetiapine. It acts as a phosphorylating agent involved in nucleoside synthesis. It plays an important role in Vilsmeier formylation and glyoxylation reactions.
Diphosphoryl chloride Preparation Products And Raw materials
Raw materialsChlorine-->Phosphorus pentoxide
Preparation Products2-Chloroadenine
Methylene Chloride Boron oxide Yttrium oxide Calcium chloride COBALT(III) OXIDE BLACK Acryloyl chloride Dititanium trioxide Bismuth trioxide THIOPHOSPHORYL CHLORIDE Choline chloride Chloroacetyl chloride Pivaloyl chloride Sulfuryl chloride Ammonium chloride Diethyl chlorothiophosphate Oxalyl chloride Benzoyl chloride Thionyl chloride

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