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| | (±)17-HETE Basic information |
| Product Name: | (±)17-HETE | | Synonyms: | (±)17-HETE;OPPIPPRXLIDJKN-JPURVOHMSA-N;5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (5Z,8Z,11Z,14Z)-;17-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid | | CAS: | 128914-47-6 | | MF: | C20H32O3 | | MW: | 320.47 | | EINECS: | | | Product Categories: | | | Mol File: | 128914-47-6.mol |  |
| | (±)17-HETE Chemical Properties |
| storage temp. | Store at -20°C | | solubility | 0.1 m Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml |
| | (±)17-HETE Usage And Synthesis |
| Description | Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive. | | Definition | ChEBI: A HETE that consists of arachidonic acid bearing an additional hydroxy substituent at position 17. |
| | (±)17-HETE Preparation Products And Raw materials |
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